Targeting Undruggable Protein Interactions with DNA Aptamers: Inhibition of the Interaction Between <i>Yersinia</i> Outer Protein M and Human DEAD-Box Helicase 3. [PDF]
Gök O, Uğurlu Ö, Özyurt C, Evran S.
europepmc +1 more source
Complex SELEX: Stochastic Modeling, Simulation and Analysis
指數富集的配體有系統演化(Systematic Evolution of Ligands by Exponential enrichment(SELEX))是一個在高度複雜的核酸分子庫中,以反覆的篩選及放大和目標分子(target)接合的配體(ligand)的一種重要的分子生物技術,而此與目標分子接合的配體我們稱之為適合體(aptamer)。近來在生物研究及藥品開發上,已提升至在核酸分子庫中同時挑選與多目標分子接合的配體實驗。為了了解此實驗 ...
Chao, Chia-Chi, 趙佳琪
core
Combined Target-Immobilized and Library-Immobilized SELEX for Selecting High-Affinity α-Amanitin Aptamers. [PDF]
Li Y +8 more
europepmc +1 more source
Research advances in aptamers in the diagnosis and treatment of breast cancer (Review). [PDF]
Chu L +6 more
europepmc +1 more source
RNA-binding protein transcripts reflect composition of target mRNAs. [PDF]
Kapral TH, Žagrović B.
europepmc +1 more source
De novo design of functional nucleic acids of aptamers. [PDF]
Zhang Z +9 more
europepmc +1 more source
Aptamer-Functionalized Nanocarriers for Bone and Joint Diseases: Engineering Design Rules and Translational Roadmap. [PDF]
Al-Azzani H +5 more
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CEMs-SELEX: DNAzyme-powered de novo biomarker discovery and noninvasive cancer diagnosis. [PDF]
Cui W +9 more
europepmc +1 more source
Exploiting conformational changes in a caffeine aptamer to engineer synthetic RNA devices. [PDF]
Kraus L +9 more
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