Results 251 to 258 of about 56,769 (258)
Some of the next articles are maybe not open access.
Self-amplifying RNA virus vectors for drug delivery
Expert Opinion on Drug DeliveryViral vectors have proven useful for delivering genetic information, such as drugs and vaccines, for therapeutic and prophylactic interventions. Self-amplifying RNA viruses possess the special feature of high-level RNA amplification in the host cell cytoplasm providing high antigen production against infectious pathogens and various types of cancers ...
openaire +2 more sources
The recent COVID-19 pandemic as well as other past and recent outbreaks of newly or re-emerging viruses show the urgent need to develop potent new vaccine approaches, that enable a quick response to prevent global spread of infectious diseases. The breakthrough of first messenger RNA (mRNA)-based vaccines 2019 approved only months after identification ...
Louisa, Zimmermann, Stephanie, Erbar
openaire +2 more sources
Louisa, Zimmermann, Stephanie, Erbar
openaire +2 more sources
Development of a self-amplifying RNA vaccine against Rift Valley fever
Background: Rift Valley fever (RVF) is a mosquito-borne zoonosis caused by the Rift Valley fever virus (RVFV), which leads to high mortality in livestock and severe or fatal complications in humans. Despite its severity, no licensed RVF vaccine exists for humans, and licensed livestock vaccines have suboptimal safety and immunogenicity.openaire +1 more source
Self-amplifying RNA in lipid nanoparticles: a next-generation vaccine?
Nature Reviews Drug Discovery, 2012openaire +1 more source
Investigating alternative delivery systems for self-Amplifying RNA vaccines
2019openaire +1 more source
Vaccines: Self-amplifying RNA in lipid nanoparticles: a next-generation vaccine?
Nature reviews. Drug discovery, 2012openaire +1 more source