Results 91 to 100 of about 51,073 (189)

Encapsulation of zingerone by self-assembling peptides derived from fish viscera: Characterization, interaction and effects on colon epithelial cells

Food Chemistry: X
The purpose of the present work was to encapsulate zingerone (a bioactive compound from ginger) by self-assembling peptides derived from fish viscera. The encapsulation conditions were investigated and the structure of fish peptides-zingerone complex was
Sirong Huang, Xintong Yao, Boya Cao, Na Zhang, Olugbenga P. Soladoye, Yuhao Zhang, Yu Fu   +6 more
doaj   +1 more source

Enhanced sampling of multidimensional free-energy landscapes using adaptive biasing forces

, 2010
We propose an adaptive biasing algorithm aimed at enhancing the sampling of multimodal measures by Langevin dynamics. The underlying idea consists in generalizing the standard adaptive biasing force method commonly used in conjunction with molecular ...
Chipot, Chris, Lelièvre, Tony
core   +3 more sources

Assessing cellular response to functionalized α-helical peptide hydrogels [PDF]

, 2014
α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization.
Abelardo, Edgardo, Birchall, Martin A, Hudson, Kieran L, Mehrban, Nazia, Mullen, Leanne M, Thomson, A R, Wasmuth, Alexandra, Woolfson, Derek N   +7 more
core   +4 more sources

Characterization of self-assembling peptide nanofibers of KLD12 and RID 12 [PDF]

, 2004
Thesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2004.Includes bibliographical references (p. 70-72).Self-assembling peptides are a promising new area of research with usage in numerous areas, from tissue ...
Dai, Jessica, 1981-
core  

Recent progress in mitochondria-targeted drug and drug-free agents for cancer therapy [PDF]

, 2019
The mitochondrion is a dynamic eukaryotic organelle that controls lethal and vital functions of the cell. Being a critical center of metabolic activities and involved in many diseases, mitochondria have been attracting attention as a potential target for
Jeena, M.T., Jin, Seongeon, Kim, Sangpil, Ryu, Ja-Hyoung   +3 more
core   +1 more source

Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo

International Journal of Nanomedicine, 2012
Yan Wu,1,* Parisa Sadatmousavi,2,* Rong Wang,1 Sheng Lu,2 Yong-fang Yuan,1 P. Chen21Department of Pharmacy, No. 3 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China ...
Wu Y, Sadatmousavi P, Wang R, Lu S, Yuan YF, Chen P   +5 more
doaj  

Functional Peptide-Based Biomaterials for Pharmaceutical Application: Sequences, Mechanisms, and Optimization Strategies

Journal of Functional Biomaterials
Peptide-based biomaterials have emerged as versatile tools for pharmaceutical drug delivery due to their biocompatibility and tunable sequences, yet a comprehensive overview of their categories, mechanisms, and optimization strategies remains lacking to ...
Dedong Yu, Nari Han, Hyejeong Son, Sun Jo Kim, Seho Kweon   +4 more
doaj   +1 more source

Furin-Triggered Peptide Self-Assembly Activates Coumarin Excimer Fluorescence for Precision Live-Cell Imaging

Molecules
Monomer-to-excimer transition has become a valuable technique in fluorescence imaging because of its ability to enhance imaging contrast. However, from a practical perspective, the accuracy of excimer formation at target sites warrants further ...
Peiyao Chen, Liling Meng, Yuting Wang, Xiaoya Yan, Meiqin Li, Yun Deng, Yao Sun   +6 more
doaj   +1 more source

A Two-Piece Derivative of a Group I Intron RNA as a Platform for Designing Self-Assembling RNA Templates to Promote Peptide Ligation

Journal of Nucleic Acids, 2012
Multicomponent RNA-peptide complexes are attractive from the viewpoint of artificial design of functional biomacromolecular systems. We have developed self-folding and self-assembling RNAs that serve as templates to assist chemical ligation between two ...
Takahiro Tanaka, Hiroyuki Furuta, Yoshiya Ikawa   +2 more
doaj   +1 more source

Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction

Nature Communications, 2017
Spatiotemporal control of intracellular molecular self-assembly holds promise for therapeutic applications. Here the authors develop a peptide consisting of a phenylalanine dipeptide with a mitochondrial targeting moiety to form self-assembling fibrous ...
M. T. Jeena, L. Palanikumar, Eun Min Go, Inhye Kim, Myoung Gyun Kang, Seonik Lee, Sooham Park, Huyeon Choi, Chaekyu Kim, Seon-Mi Jin, Sung Chul Bae, Hyun Woo Rhee, Eunji Lee, Sang Kyu Kwak, Ja-Hyoung Ryu   +14 more
doaj   +1 more source