Results 51 to 60 of about 177,835 (279)

Self-assembled guanine ribbons as wide-bandgap semiconductors

, 2001
We present a first principle study about the stability and the electronic properties of a new biomolecular solid-state material, obtained by the self-assembling of guanine (G) molecules.
A. Calzolari, A. Garbesi, Becke, Braun, Dreizler, E. Molinari, Giese, Gottarelli, Jortner, Kelley, Kelley, Lee, Porath, Pugh, R. Di Felice, Rinaldi, Saenger, Schuster, Troullier, Ye, Šponer   +20 more
core   +1 more source

Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(N-Alkylpyridinium)-1,4-Dihydropyridines

Pharmaceutics, 2019
The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(N-alkylpyridinium)-1,4-dihydropyridine (1,4-DHP) derivatives ...
Martins Rucins, Pavels Dimitrijevs, Klavs Pajuste, Oksana Petrichenko, Ludmila Jackevica, Anita Gulbe, Signe Kibilda, Krisjanis Smits, Mara Plotniece, Dace Tirzite, Karlis Pajuste, Arkadij Sobolev, Janis Liepins, Ilona Domracheva, Aiva Plotniece   +14 more
doaj   +1 more source

Using the uncertainty principle to design simple interactions for targeted self-assembly [PDF]

, 2012
We present a method that systematically simplifies isotropic interactions designed for targeted self-assembly. The uncertainty principle is used to show that an optimal simplification is achieved by a combination of heat kernel smoothing and Gaussian ...
Badii R., E. Edlund, M. Nilsson Jacobi, O. Lindgren   +3 more
core   +2 more sources

Emergent mechanical properties of self-assembled polymeric capsules [PDF]

Proceedings of the National Academy of Sciences, 2000
Synthetic self-assembled systems combine responsiveness and reversibility with the ability to perform chemical tasks such as molecular recognition and catalysis. An unmet challenge is the construction of polymeric materials that, like nature's tubulin, are simultaneously reversible and capable of useful physical
R K, Castellano, R, Clark, S L, Craig, C, Nuckolls, J, Rebek   +4 more
openaire   +2 more sources

Polymorphic Ring-Shaped Molecular Clusters Made of Shape-Variable Building Blocks

Nanomaterials, 2015
Self-assembling molecular building blocks able to dynamically change their shapes, is a concept that would offer a route to reconfigurable systems. Although simulation studies predict novel properties useful for applications in diverse fields, such kinds
Keitel Cervantes-Salguero, Shogo Hamada, Shin-ichiro M. Nomura, Satoshi Murata   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development of Self-Assembling bis-1,4-Dihydropyridines: Detailed Studies of Bromination of Four Methyl Groups and Bromine Nucleophilic Substitution

Molecules, 2023
One of the most important steps in the synthesis of 1,4-dihydropyridine (1,4-DHP) amphiphiles is the bromination of methyl groups in positions 2 and 6 of the entire ring.
Martins Kaukulis, Martins Rucins, Davis Lacis, Aiva Plotniece, Arkadij Sobolev   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

HydrogelFinder: A Foundation Model for Efficient Self‐Assembling Peptide Discovery Guided by Non‐Peptidal Small Molecules

Advanced Science
Self‐assembling peptides have numerous applications in medicine, food chemistry, and nanotechnology. However, their discovery has traditionally been serendipitous rather than driven by rational design.
Xuanbai Ren, Jiaying Wei, Xiaoli Luo, Yuansheng Liu, Kenli Li, Qiang Zhang, Xin Gao, Sizhe Yan, Xia Wu, Xingyue Jiang, Mingquan Liu, Dongsheng Cao, Leyi Wei, Xiangxiang Zeng, Junfeng Shi   +14 more
doaj   +1 more source

Novel Benzothiazole Boc-Phe-Phe-Bz Derivative Dipeptide Forming Fluorescent and Nonlinear Optical Self-Assembled Structures

Molecules
This work explores the self-assembly and optical properties of a novel chiral, aromatic-rich Boc-Phe-Phe dipeptide derivative functionalized with a benzothiazole bicyclic ring that forms supramolecular structures.
Rosa M. F. Baptista, Daniela Santos, N. F. Cunha, Maria Cidália R. Castro, Pedro V. Rodrigues, Ana V. Machado, Michael S. Belsley, Etelvina de Matos Gomes   +7 more
doaj   +1 more source