Results 51 to 60 of about 9,846,676 (255)

HydrogelFinder: A Foundation Model for Efficient Self‐Assembling Peptide Discovery Guided by Non‐Peptidal Small Molecules

Advanced Science
Self‐assembling peptides have numerous applications in medicine, food chemistry, and nanotechnology. However, their discovery has traditionally been serendipitous rather than driven by rational design.
Xuanbai Ren, Jiaying Wei, Xiaoli Luo, Yuansheng Liu, Kenli Li, Qiang Zhang, Xin Gao, Sizhe Yan, Xia Wu, Xingyue Jiang, Mingquan Liu, Dongsheng Cao, Leyi Wei, Xiangxiang Zeng, Junfeng Shi   +14 more
doaj   +1 more source

Novel Benzothiazole Boc-Phe-Phe-Bz Derivative Dipeptide Forming Fluorescent and Nonlinear Optical Self-Assembled Structures

Molecules
This work explores the self-assembly and optical properties of a novel chiral, aromatic-rich Boc-Phe-Phe dipeptide derivative functionalized with a benzothiazole bicyclic ring that forms supramolecular structures.
Rosa M. F. Baptista, Daniela Santos, N. F. Cunha, Maria Cidália R. Castro, Pedro V. Rodrigues, Ana V. Machado, Michael S. Belsley, Etelvina de Matos Gomes   +7 more
doaj   +1 more source

Supramolecular Nanostructures Based on Perylene Diimide Bioconjugates: From Self-Assembly to Applications

Nanomaterials, 2022
Self-assembling π-conjugated systems constitute efficient building blocks for the construction of supramolecular structures with tailored functional properties.
Nadjib Kihal, Ali Nazemi, Steve Bourgault   +2 more
doaj   +1 more source

On the Emulsifying Properties of Self-Assembled Pea Protein Particles [PDF]

Langmuir, 2020
Pea proteins are promising oil-in-water emulsifying agents at both neutral and acidic conditions. In an acidic environment, pea proteins associate to form submicrometer-sized particles. Previous studies suggested that the emulsions at acidic pH were stabilized due to a Pickering mechanism.
Sridharan, Simha, Meinders, Marcel B.J., Bitter, Johannes H., Nikiforidis, Constantinos V.   +3 more
openaire   +3 more sources

Computational Prediction of the Supramolecular Self-Assembling Properties of Organic Molecules: Flexibility vs Rigidity [PDF]

, 2021
Two families of organic molecules with different backbones have been considered. The first family, composed by a substituted central phenyl is considered as flexible. The second one, based on a macrolactam-like unit, is considered as rigid.
Laura, Le Bras, Yves L., Dory, Benoît, CHAMPAGNE   +2 more
core   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Recent Advances on Supramolecular Gels: From Stimuli-Responsive Gels to Co-Assembled and Self-Sorted Systems

Organic Materials, 2021
Gels prepared from low-molecular-weight gelators (LMWGs) represent versatile soft materials. Self-assembly of LMWGs forms nanofibers and above critical gelation concentrations, the entanglement of which leads to self-supporting gels. Owing to the dynamic
Chih-Wei Chu, Christoph A. Schalley
doaj   +1 more source

Self-Assembling Peptide Epitopes as Novel Platform for Anticancer Vaccination [PDF]

, 2017
The aim of the present study was to improve the immunogenicity of peptide epitope vaccines using novel nanocarriers based on self-assembling materials.
Bourajjaj, Meriem, Pharmaceutics, Wim E. Hennink (290165), Mazda Rad-Malekshahi (1578544), Krawczyk, Małgorzata, Chen, Jian, Małgorzata Krawczyk (3699184), Jian Chen (15340), Mercedeh Mansourian (3699190), Radmalekshahi, Mazda, Maryam Amidi (3699187), Mansourian, Mersedeh, Dep Farmaceutische wetenschappen, Ferry Ossendorp (230155), Fransen, Marieke F, Enrico Mastrobattista (712060), Hennink, Wim E, Ossendorp, Ferry, Marieke F. Fransen (3699181), Meriem Bourajjaj (318743), Afd Pharmaceutics, Amidi, Maryam, Mastrobattista, Enrico   +22 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Mechanics and kinetics of dynamic instability

eLife, 2020
During dynamic instability, self-assembling microtubules (MTs) stochastically alternate between phases of growth and shrinkage. This process is driven by the presence of two distinct states of MT subunits, GTP- and GDP-bound tubulin dimers, that have ...
Thomas CT Michaels, Shuo Feng, Haiyi Liang, L Mahadevan   +3 more
doaj   +1 more source