Results 71 to 80 of about 18,428 (265)
International Journal of Concrete Structures and MaterialsTo minimize the seismic damage to the beam-column joint and facilitate post-earthquake repair, an innovative precast concrete (PC) beam-column joint (SCPJ) with self-centering and damage-controllable capacities was proposed.
Chunxu Hou +4 more
doaj +1 more source
Resilient Cities and StructuresSelf-Centering Piston-Based Braced Frames (SC-PBBFs) are designed to curtail structural damage under severe ground motions. The self-centering mechanism in this bracing mitigates structural damage during an earthquake, thereby reducing post-earthquake ...
Navid Rahgozar, M.Shahria Alam
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Self-Centering Shape Memory Alloy-Viscoelastic Hybrid Braces for Seismic Resilience. [PDF]
Materials (Basel), 2022 Zhang ZX, Ping Y, He X.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
A Novel Dual Self-Centering Friction Damper for Seismic Responses Control of Steel Frame
BuildingsDue to their weight, the seismic response control of buildings needs a large-scale damper. To reduce the consumption of shape memory alloys (SMAs), this study proposed a dual self-centering pattern accomplished by the coil springs and SMA, which could ...
Juntong Qu +6 more
doaj +1 more source
Experimental Study on Self-Centering Performance of the SMA Fiber Reinforced ECC Composite Beam. [PDF]
Materials (Basel), 2022 Yang Z, Deng T, Li J, Xu C.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Performance-Based Assessment of Bridges with Novel SMA-Washer-Based Self-Centering Rocking Piers. [PDF]
Materials (Basel), 2022 Chen J, Liang D, You X, Liang H.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source