Results 71 to 80 of about 5,400,453 (323)

13C-Methyl isocyanide as an NMR probe for cytochrome P450 active site [PDF]

, 2009
The cytochromes P450 (CYPs) play a central role in many biologically important oxidation reactions, including the metabolism of drugs and other xenobiotic compounds.
Im, Sang-Choul, McCullough, Christopher R, Pullela, Phani Kumar, Sem, Daniel S., Waskell, Lucy   +4 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Norway as a Battery for the Future European Power System—Impacts on the Hydropower System

Energies, 2017
Future power production in Europe is expected to include large shares of variable wind and solar power production. Norway, with approximately half of the hydropower reservoir capacity in Europe, can contribute to balance the variability.
Ingeborg Graabak, Stefan Jaehnert, Magnus Korpås, Birger Mo   +3 more
doaj   +1 more source

Resiliência: o livreiro do Alemão [PDF]

, 2016
O programa Sem Censura aborda o tema resiliência entrevistando o escritor negro Otávio Júnior, morador da comunidade do Complexo do Alemão no Rio de ...
SEM CENSURA
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Applying SEM, Exploratory SEM, and Bayesian SEM to Personality Assessments

Psych
Despite the importance of demonstrating and evaluating how structural equation modeling (SEM), exploratory structural equation modeling (ESEM), and Bayesian structural equation modeling (BSEM) work simultaneously, research comparing these analytic techniques is limited with few studies conducted to systematically compare them to each other using ...
Hyeri Hong, Walter Vispoel, Alfonso Martinez   +2 more
openaire   +2 more sources

SEM

Revista Debates Insubmissos, 2023
Poema
openaire   +1 more source

Raman Spectroscopic and SEM Analysis of Sodium-Zippeite [PDF]

, 2007
Raman at 298 and 77 K and infrared spectra of two samples of sodium-zippeite were studied and interpreted. U-O bond lengths in uranyl were calculated and compared with those inferred from the X-ray single crystal structure data of a synthetic sodium ...
Anderson, Bartlett, Burns, Burns, Burns, Burns, Cejka, Cejka, Elton, Finch, Frondel, Frondel, Frondel, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Frost, Gaines, Haacke, Hawthorne, Hawthorne, Hawthorne, Hawthorne, Hoekstra, Libowitzky, McCollam, Meisser, O'Brien, Ondrus, Paulis, Sejkora, Serezhkin, Volod'ko   +43 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Peirce, meaning and the semantic web [PDF]

, 2007
The so-called ‘Semantic Web’ is phase II of Tim Berners-Lee’s original vision for the WWW, whereby resources would no longer be indexed merely ‘syntactically’, via opaque character-strings, but via their meanings.
Legg, Catherine
core   +2 more sources