Results 71 to 80 of about 4,907,732 (327)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Revista Literária do Corpo Discente da Universidade Federal de Minas Gerais, 1994 .
openaire +3 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Non-linear fire-resistance analysis of reinforced concrete beams [PDF]
, 2003 The non-linear structural analysis of reinforced concrete beams in fire consists of three separate steps: (i) The estimation of the rise of surrounding air temperature due to fire; (ii) the determination of the distribution of the temperature within the ...
Bratina, Sebastjan +3 more
core +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Low carbon power generation for offshore oil and gas production
Energy Conversion and Management: X, 2023 Emission reductions in power generation for offshore oil and gas activities are key in order to reach climate targets in regions with this industry. This study presents a review of both established and immature low carbon power generation concepts, an ...
Mari Voldsund +9 more
doaj
Resiliência: o livreiro do Alemão [PDF]
, 2016 O programa Sem Censura aborda o tema resiliência entrevistando o escritor negro Otávio Júnior, morador da comunidade do Complexo do Alemão no Rio de ...
SEM CENSURA
core
Assessment of FEMA356 nonlinear static procedure and modal pushover analysis for seismic evaluation of buildings [PDF]
, 2012 Nonlinear static analysis as an essential part of performance based design is now widely used especially at design offices because of its simplicity and ability to predict seismic demands on inelastic response of buildings.
Khoshnoud, Hamid Reza +1 more
core +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source