Results 181 to 190 of about 234,767 (218)
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Overexpression of semaphorin 3A in patients with urothelial cancer

Urologic Oncology: Seminars and Original Investigations, 2018
A highly sensitive and specific urine marker for the detection of recurrent urothelial cancer and for screening healthy population or people at risk for urothelial cancer has not been found yet. As urine cytology is not sensitive enough, patients with non-muscle-invasive bladder cancer need lifelong follow-up involving multiple invasive cystoscopies ...
Zahava, Vadasz   +4 more
openaire   +2 more sources

Semaphorin-3A: a promising therapeutic tool in allergic rhinitis

Immunologic Research, 2022
Semaphorin-3A (Sema-3A), a secreted member of the semaphorin family, is well known for playing regulatory functions at all stages of the immune response. Sema-3A transduces signals by binding to its cognate receptors, namely, class A plexins (Plxns A1 to A4) and neuropilin-1 (Nrp-1).
Ramin Lotfi, Nahid Zamanimehr
openaire   +2 more sources

Role of Semaphorin 3A in common psychiatric illnesses such as schizophrenia, depression, and anxiety.

Biochemical Pharmacology
With societal development and an ageing population, psychiatric disorders have become a common cause of severe and long-term disability and socioeconomic burdens worldwide.
Yang Yang   +3 more
semanticscholar   +1 more source

Nerve growth factor (Ngf) gene-driven semaphorin 3a (Sema3a) expression exacerbates thoracic aortic aneurysm dissection in mice

Journal of Hypertension, 2023
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening disease and currently there is no pharmacological therapy. Sympathetic nerve overactivity plays an important role in the development of TAAD.
Lifei Wu   +13 more
semanticscholar   +1 more source

Emerging role of semaphorin-3A in autoimmune diseases

Inflammopharmacology, 2018
Autoimmune diseases (ADs) are featured by the body's immune responses being directed against its own tissues, resulting in prolonged inflammation and subsequent tissue damage. Currently, the exact pathogenesis of ADs remains not fully elucidated. Semaphorin-3A (Sema3A), a secreted member of semaphorin family, is a potent immunoregulator during all ...
Li-Na, Liu   +3 more
openaire   +2 more sources

Naringin activates semaphorin 3A to ameliorate TGF‐β‐induced endothelial‐to‐mesenchymal transition related to atrial fibrillation

Journal of Cellular Physiology
The loss of semaphorin 3A (Sema3A), which is related to endothelial‐to‐mesenchymal transition (EndMT) in atrial fibrosis, is implicated in the pathogenesis of atrial fibrillation (AF).
Ying-Ju Lai   +7 more
semanticscholar   +1 more source

Semaphorin 3A influences neuronal processes that are altered in patients with autism spectrum disorder: potential diagnostic and therapeutic implications.

Neuroscience and Biobehavioral Reviews, 2023
Autism spectrum disorder (ASD) is a pervasive disorder that most frequently manifests in early childhood and lasts for their entire lifespan. Several behavioural traits characterise the phenotype of patients with ASD, including difficulties in reciprocal
C. Matrone, G. Ferretti
semanticscholar   +1 more source

Semaphorin 3A: Is a key player in the pathogenesis of asthma

Clinical Immunology, 2017
Immune semaphorins are key players in regulating immune mediated inflammation. Semaphorin3A (sema3A) a secreted and membrane bound member of this family, is well reported for its properties in maintaining self-tolerance. Semaphorin3A was recognized to be a marker for T-regulatory cells (Tregs), and as such is a useful tool for assessing the status of ...
Ronen, Cozacov   +3 more
openaire   +2 more sources

A Study on Semaphorin 3A Level in Juvenile-onset Systemic Lupus Erythematosus Patients.

Current Rheumatology Reviews
BACKGROUND Juvenile-onset systemic lupus erythematosus (jSLE) is an uncommon yet severe autoimmune/inflammatory condition affecting multiple bodily systems, typically manifest-ing before the age of 18.
Huda Marzouk   +4 more
semanticscholar   +1 more source

Semaphorin 3A-mediated perineuronal nets formation incubates depressive-like behaviors in male mice via activating parvalbumin-expressing interneurons

Molecular Psychiatry
Yuan Mei   +10 more
semanticscholar   +1 more source

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