Results 171 to 180 of about 9,266 (196)
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Regulation of dendritic length and branching by semaphorin 3A
Journal of Neurobiology, 2004AbstractThe molecular mechanisms that control dendritic development are still unclear. Semaphorin 3A, a class III semaphorin, has been shown to regulate the radial orientation of pyramidal neurons in the developing neocortex. Here, we investigate the effects of Sema3A on the development of dendritic topology.
Vivian, Fenstermaker +3 more
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Overexpression of semaphorin 3A in patients with urothelial cancer
Urologic Oncology: Seminars and Original Investigations, 2018A highly sensitive and specific urine marker for the detection of recurrent urothelial cancer and for screening healthy population or people at risk for urothelial cancer has not been found yet. As urine cytology is not sensitive enough, patients with non-muscle-invasive bladder cancer need lifelong follow-up involving multiple invasive cystoscopies ...
Zahava, Vadasz +4 more
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Semaphorin 3A on Osteoporosis: An Overreview of the Literature
Calcified Tissue InternationalSemaphorin 3A (Sema3A) is a signaling protein that has attracted increasing attention in recent years for its important role in regulating bone metabolism. In this review, we searched different databases with various combinations of keywords to analyze the effects of Sema3A on osteoporosis. Sema3A promotes bone formation and inhibits bone resorption by
Yueyi Zhang +12 more
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Emerging role of semaphorin-3A in autoimmune diseases
Inflammopharmacology, 2018Autoimmune diseases (ADs) are featured by the body's immune responses being directed against its own tissues, resulting in prolonged inflammation and subsequent tissue damage. Currently, the exact pathogenesis of ADs remains not fully elucidated. Semaphorin-3A (Sema3A), a secreted member of semaphorin family, is a potent immunoregulator during all ...
Li-Na, Liu +3 more
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Semaphorin 3A: Is a key player in the pathogenesis of asthma
Clinical Immunology, 2017Immune semaphorins are key players in regulating immune mediated inflammation. Semaphorin3A (sema3A) a secreted and membrane bound member of this family, is well reported for its properties in maintaining self-tolerance. Semaphorin3A was recognized to be a marker for T-regulatory cells (Tregs), and as such is a useful tool for assessing the status of ...
Ronen, Cozacov +3 more
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Differential impact of semaphorin 3E and 3A on CNS axons
International Journal of Developmental Neuroscience, 2005AbstractDuring the development of the central nervous system (CNS), the correct wiring of outgrowing neurites is mediated by antagonistic mechanisms. Aberrant growth is prevented by repulsive factors such as semaphorins. Expression of the ligands Sema3A and ‐3E and the receptors neuropilin Npn‐1, ‐2a and ‐2b in the chick visual system were analyzed by ...
Steffensky, M. +3 more
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Structural basis of semaphorin‐plexin cis interaction
EMBO Journal, 2020Daniel Rozbeský +2 more
exaly
Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance
Cell, 2019Agatha A Van Der Klaauw +2 more
exaly