Results 101 to 110 of about 4,625 (132)

Semaphorin 3C preserves survival and induces neuritogenesis of cerebellar granule neurons in culture

Journal of Neurochemistry, 2003
AbstractSemaphorins (sema) constitute a family of molecules sharing a common extracellular domain (semaphorin domain). This family includes several types of secreted and membrane‐associated molecules that are grouped into eight subclasses (subclasses 1–7 and viral semaphorins).
Moreno-Flores, M T, Martin-Aparicio, E, Martin-Bermejo, M J, Agudo, M, McMahon, S, Avila, J, Diaz-Nido, J, Wandosell, F   +7 more
openaire   +4 more sources

Renal Semaphorin 3C mediates cardiac adaptive response

European Heart Journal
Abstract   Cardiorenal syndrome, characterized by reciprocal heart-kidney interactions that progressively promote dysfunction in both organs, is associated with a high mortality rate. However, the mechanisms linking the two organs are insufficiently understood.
Y Otaki, I M Manabe, T W Watanabe, T A Aono, J S Sato, S T Tachibana, Y K Kobayashi, M W Watanabe   +7 more
openaire   +1 more source

Semaphorin-3C Is Upregulated in Polycystic Kidney Epithelial Cells and Inhibits Angiogenesis of Glomerular Endothelial Cells

American Journal of Nephrology, 2020
<b><i>Background:</i></b> Polycystic kidney disease (PKD) is a hereditary disease characterized by cyst formation in the kidneys bilaterally. It has been observed that semaphorin-3C (SEMA3C) is overexpressed in polycystic kidney epithelial cells.
Bo Hye, Kim, Do Yeon, Kim, Yejin, Ahn, Eun Ji, Lee, Hyunjoo, Park, Meeyoung, Park, Jong Hoon, Park   +6 more
openaire   +2 more sources

Abstract A45: Semaphorin 3C mediates glioma stem cell tumorigenicity and radioresistance

Cancer Research, 2015
Abstract Purpose: Different cancer cell compartments often communicate through soluble factors to facilitate tumor growth. Glioma stem cells (GSCs) are a subset of tumor cells that resist standard therapy to contribute to disease progression. How GSCs employ a distinct secretory program to communicate with and nurture each other over the
Jennifer Yu, Jianghong Man, Shoemake Jocelyn, Wu Qiulian, Jeremy Rich, Shideng Bao   +5 more
openaire   +1 more source

Abstract 2256: Semaphorin 3C has a possibility of a new prognostic marker in colorectal cancer

Cancer Research, 2017
Abstract Background: Generally, Semaphorins are secretary or transmembrane-bound molecules that act as axon guidance cues in the nervous system. Recent research showed increased expression of semaphorin 3C correlates with cancers that possess higher invasive and metastatic characteristics.
Shingo Kawano, Kota Amemiya, Yuki Tsuchiya, Toshiaki Hagiwara, Hirokazu Matsuzawa, Yurika Makino, Shunsuke Motegi, Ryoichi Tsukamoto, Ryosuke Ichikawa, Kazumasa Kure, Kumpei Honjo, Hisashi Ro, Shingo Ito, Yu Okazawa, Rina Takahashi, Kosuke Mizukoshi, Masaya Kawai, Shinya Munakata, Koichiro Niwa, Shun Ishiyama, Kiichi Sugimoto, Hirohiko Kamiyama, Hiromitsu Komiyama, Makoto Takahashi, Yutaka Kojima, Michitoshi Goto, Atsushi Okuzawa, Yuichi Tomiki, Kazuhiro Sakamoto, Motohiro Kojima, Atsushi Ochiai   +30 more
openaire   +1 more source

Identifying semaphorin 3C as a biomarker for sarcopenia and coronary artery disease via bioinformatics and machine learning

Archives of Gerontology and Geriatrics
Sarcopenia not only affects patients' quality of life but also may exacerbate the pathological processes of coronary artery disease (CAD). This study aimed to identify potential biomarkers to improve the combined diagnosis and treatment of sarcopenia and CAD.Datasets for sarcopenia and CAD were sourced from the Gene Expression Omnibus (GEO).
Shu Ran, Zhuoqi Li, Xitong Lin, Baolin Liu   +3 more
openaire   +2 more sources

Semaphorin 3c (SEMA3C) as a potential therapeutic target in breast cancer

Breast cancer (BCa) is a significant cause of cancer-related deaths among females globally. Approximately 45% of BCa patients develop treatment resistance or suffer from a lack of targeted therapies. Previously, we have shown that Semaphorin 3C (SEMA3C) is an autocrine growth factor that drives the growth and treatment resistance of various cancers ...
openaire   +1 more source

Semaphorin 3C Mediates Glioma Stem Cell Tumorigenicity

International Journal of Radiation Oncology*Biology*Physics, 2015
J.S. Yu, J. Man, J. Shoemake, S. Bao, Q. Wu, J. Rich   +5 more
openaire   +1 more source

Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins

Cell, 2020
Iga Kucharska, Jean-Philippe Julien, Daniel Schramek   +2 more
exaly  

Structural basis of semaphorin‐plexin cis interaction

EMBO Journal, 2020
Daniel Rozbeský, Dimple Karia, Yvonne Jones   +2 more
exaly