Results 81 to 90 of about 4,718 (156)

plexin-A4/plexin-D1 complexes convey semaphorin-3C signals to induce cytoskeletal collapse in the absence of neuropilins

, 2018
Class-3 semaphorin guidance factors bind to receptor complexes containing neuropilin and plexin receptors. A semaphorin may bind to several receptor complexes containing somewhat different constituents, resulting in diverse effects on cell migration ...
Ofra Kessler, Gera Neufeld, Tatyana Smolkin, Inbal Nir-Zvi, Yelena Mumblat, Nerri Duvshani   +5 more
core   +1 more source

Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways.

, 2008
Contains fulltext : 69433.pdf (Publisher’s version ) (Closed access)The neuropilin (Nrp)1 receptor is essential for both nervous and vascular system development. Nrp1 is unusually versatile, because it transmits both chemoattractive and
Simons, M., D. Mukhopadhyay, M. Liu, Horowitz, A., L. Wang, Salikhova, A., Liu, M., Lanahan, A.A., Leenders, W.P.J., W. P. J. Leenders, Wang, L., M. Simons, A. A. Lanahan, Mukhopadhyay, D., A. Horowitz, A. Salikhova   +15 more
core   +1 more source

Modulation of semaphorin 3C & 4D expression in cancerous tissues from individuals with laryngeal squamous cell carcinoma. [PDF]

Indian J Med Res, 2023
Sajadian M, Khademi B, Moinzadeh L, Ghaderi A, Jafarzadeh A, Razmkhah M.   +5 more
europepmc   +1 more source

The functions of class 3 semaphorins in axon guidance and cardiac development

, 2000
In order to establish the architecture of the nervous system, neurons must connect with their targets. A search for cues that help guide growth cones resulted in the purification and cloning of a chemorepellent, semaphorin 3A.
Feiner, Leonard
core  

Der Einfluss von Semaphorin 3A und Semaphorin 3C auf das Wachstumsverhalten cortikaler Axone während der embryonalen Entwicklung des Gehirns [PDF]

, 2008
Während der embryonalen Entwicklung des Nervensystems müssen auswachsende Axone den korrekten Weg zu ihrer Zielstruktur im Gehirn finden. Verschiedene axonale Lenkungsmoleküle steuern die Navigation der wachsenden Axone.
Rüdiger, Tina
core  

The Role of CHD7 in the Transcriptional Control of Heart Development

, 2015
Chromatin remodelling provides a key mechanism for the regulation of gene expression through dynamic alterations in nucleosome occupancy at promoters and enhancers.
Payne, SA
core  

Expression, regulation and roles of semaphorins and their receptors in prostate and prostate cancer. [PDF]

, 2008
Prostate cancer (PCa) has become a major public health issue it is the second most common cause of cancer-related death in the UK. PCa preferentially metastasises to the bone.
Blanc, V.M.
core  

Expression of Semaphorin 3C in Breast Cancer and its Impact on Adhesion and Invasion of Breast Cancer Cells

, 2016
Background: The aim of the current study was to examine the role of semaphorin 3C (SEMA3C) in breast cancer. Materials and Methods: SEMA3C transcripts expressed by breast tissues were determined using real-time polymerase chain reaction (PCR). Knock-down
Malik, M. F. A., Davies, Eleri L., Malik, Muhammad Faraz Arshad, Davies, Eleri-Lloyd, Jiang, Wen G., Satherley, Lucy K., Jiang, Wen Guo, Satherley, Lucy, Ye, Lin   +8 more
core  

Increased density of sympathetic nerve fibers in metabolically activated fat tissue surrounding human synovium and mouse lymph nodes in arthritis

, 2011
Objective. To investigate the density of sympathetic nerve fibers in and the metabolic activation of fat tissue surrounding human synovium in rheumatoid arthritis (RA)/osteoarthritis (OA) and in the draining lymph nodes of arthritic and normal mice ...
Rauch, Luise, Torsten Lowin, Christine Wolff, Lowin, Torsten, Straub, Rainer H., Wolff, Christine, Rainer H. Straub, Susanne Klatt, Luise Rauch, Klatt, Susanne   +9 more
core   +1 more source

Differential gene expression analysis of human entorhinal cortex support a possible role of some extracellular matrix proteins in the onset of Alzheimer disease

, 2010
The onset of Alzheimer's disease (AD) has been associated with the specific vulnerability of neurons in the upper layers of the entorhinal cortex. To define the molecular characteristics of those neurons, we have used microarrays to define the gene ...
Rábano, Alberto, Ávila, Jesús, Santa María, Ismael   +2 more
core   +1 more source