Results 31 to 40 of about 59,216 (250)

Artificial intelligence model for the assessment of unstained live sperm morphology

Reproduction and Fertility
Traditional sperm morphology assessment requires staining and high magnification (100×), rendering sperm unsuitable for further use. We aimed to determine whether an in-house artificial intelligence (AI) model could reliably assess normal sperm ...
Jermphiphut Jaruenpunyasak, Prawai Maneelert, Marwan Nawae, Chainarong Choksuchat   +3 more
doaj   +1 more source

Oxidative Stress and Male Infertility: Evidence From a Research Perspective

Frontiers in Reproductive Health, 2022
Male fertility potential can be influenced by a variety of conditions that frequently coincide. Spermatozoa are particularly susceptible to oxidative damage due to their limited antioxidant capacity and cell membrane rich in polyunsaturated fatty acids ...
Bashir Ayad, Bashir Ayad, Temidayo S. Omolaoye, Nicola Louw, Yashthi Ramsunder, Bongekile T. Skosana, Peter I. Oyeipo, Peter I. Oyeipo, Stefan S. Du Plessis, Stefan S. Du Plessis   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Temporal Changes of Clomiphene on Testosterone Levels and Semen Parameters in Subfertile Men

The World Journal of Men's Health, 2023
Purpose: Clomiphene citrate (CC) is prescribed off-label in men to improve testosterone and sperm parameters, but the duration of treatment needed to reach maximal benefit remains unclear.
Tommy Jiang, John T. Sigalos, Vadim Osadchiy, Alvaro Santamaria, Michael H. Zheng, Neilufar Modiri, Keith V. Regets, Jesse N. Mills, Sriram V. Eleswarapu   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Molecular analysis of microorganisms in the semen and their impact on semen parameters

Archivio Italiano di Urologia e Andrologia, 2022
Objective: Chronic genitourinary infections can alter male fertility and even promote carcinogenic processes. This study aimed to evaluate the effect of the presence in the semen of microorganisms on semen quality. Materials and methods: Clinical symptoms and conventional and functional seminal parameters of eleven fertile donors and ten volunteers ...
Jenniffer Puerta Suárez, Juan Carlos Hernandez, Walter Dario Cardona Maya   +2 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Semen quality and determinants in 1177 male infertility clinic attendees in the central region of China [PDF]

Journal of Men's Health
Background: Infertility affects 15–20% of couples in China, with male factors accounting for nearly half of these cases. This study examines semen quality and its determinants among male infertile patients in Central China, aiming to provide a ...
Cheng Wang, Chunyan Shi, Hong Yu, Chaowu Zhan, Chao Wang, Jie Chen   +5 more
doaj   +1 more source

Associated Factors with Male Infertility: A Case Control Study [PDF]

Journal of Clinical and Diagnostic Research, 2014
Objective: Sperm analysis is an important step to evaluate and diagnose male’s infertility. The present study aimed to determine associated factors with males’ infertility by using semen analysis.
Mohammad Reza Hafezi Ahmadi, Masood Yasemi, Hadi Peyman, Karim Hemati, Javaher Khajavikhan, Monireh Yaghoubi, Lida Bimanand   +6 more
doaj   +1 more source