Results 41 to 50 of about 174,586 (294)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Artificial intelligence model for the assessment of unstained live sperm morphology

open access: yesReproduction and Fertility
Traditional sperm morphology assessment requires staining and high magnification (100×), rendering sperm unsuitable for further use. We aimed to determine whether an in-house artificial intelligence (AI) model could reliably assess normal sperm ...
Jermphiphut Jaruenpunyasak   +3 more
doaj   +1 more source

Analysis of Corporate Social Responsibility Implementation and Social Audit at PT Semen Padang [PDF]

open access: yes, 2015
This study describes the implementation of CSR and social audit in PT Semen Padang. PT Semen Padang as one of the largest states owned enterprise in West Sumatra has a big hand in the development of West Sumatra.
Edmawati, S. D. (Sri)   +1 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Adherence to WHO 2010 Recommendations in Relation to Semen Analysis Reports in the Laboratories of West Bengal

open access: yesFertility & Reproduction, 2019
Background: In 2010, The World Health Organization (WHO) suggested the standards of reporting of semen analysis and the reference values. We tried to determine the adherence to the WHO 2010 standard regarding semen analysis among the laboratories of West
Sujoy Dasgupta
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The IMPACT OF SINGLE AND MULTIPLE SPERM ABNORMALITIES AND LOW-LEVEL LEUKOCYTOSPERMIA ON SPERM DNA

open access: yesJournal of Men's Health, 2019
Background and objective The aim of the present study was to identify the impact of defective standard sperm parameters individually and in combination on DNA damage in a large cohort of infertile men.
Saad Alshahrani   +4 more
doaj   +1 more source

Comparison of five different methods to assess the concentration of boar semen [PDF]

open access: yes, 2010
Both for research and practical purposes, accurate and repeatable methods are required to assess the concentration of boar semen samples. Since the method which is used may influence the results considerably, the aim of the present study was to compare 5
Deley, W   +5 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Preoperative Predictors for the Presence of Motile Spermatozoa in the Epididymis and Patency of Anastomosis During Microsurgical Vasoepididymal Anastomosis in Patients with Obstructive Azoospermia

open access: yesJournal of Human Reproductive Sciences, 2023
Background: Following microsurgical vaso-epididymal anastomosis (VEA), anastomotic patency with sperm returning to the ejaculate is not always present and may even be delayed.
Bhopesh Kadian   +5 more
doaj   +1 more source

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