Results 51 to 60 of about 59,216 (250)
Semen Analysis and in vitro Fertilization [PDF]
Thirty-seven patients underwent ultrasonographic, clinical, and hormonal monitoring of superovulated cycles in order to time HCG administration in an attempt to schedule the laparoscopy at the optimal time for oocyte recovery. Superovulation was induced by Clomiphene in patients under the age of 35, with both ovaries; Clomiphene and HMG were ...
L, Formigli +4 more
openaire +2 more sources
Quality of Bovine Chilled or Frozen-Thawed Semen after Addition of Omega-3 Fatty Acids Supplementation to Extender [PDF]
Background: This study was conducted to evaluate the potential protective effects of omega-3 poly unsaturated fatty acids (Ω-3 PUFAs) on bovine sperm quality in response to cooling and cryopreservation.
Abbas Abavisani +4 more
doaj
Purpose: To predict the probability of azoospermia without a semen analysis in men presenting with infertility by developing an azoospermia prediction model. Materials and Methods: Two predictive algorithms were generated, one with follicle stimulating
Michael B. Tradewell +10 more
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Introduction: Infertility, defined as the inability to conceive after a year of regular unprotected sexual activity, is a significant global health concern.
Jyotshna Tiwari +4 more
doaj +1 more source
Does sperm DNA fragmentation correlate with semen parameters?
Purpose This study aimed to investigate the association between sperm quality assessed by routine semen analysis and sperm DNA integrity assay. Methods In our cross‐sectional study, a total of 318 men from the infertile couples were enrolled from ...
Minh Tam Le +7 more
doaj +1 more source
Background: Varicocele can cause progressive testicular damage and infertility. Severe retrograde blood flow to the internal spermatic vein has been suggested as a risk factor for infertility or progressive/stable varicocele. We have aimed to Compared th
Mostafa Babai +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

