Results 51 to 60 of about 175,019 (340)

Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features [PDF]

, 2015
Internal levels of selected endocrine disruptors (EDs) (i.e., perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), di-2-ethylhexyl-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and bisphenol A (BPA)) were analyzed in blood/serum of ...
Bergamasco B, Bordi G, Busani L, Caserta D, Ciardo F, Focardi S, Guerranti C, La Rocca C, Mancini FR, Mantovani A, Marci R, Moscarini M, Perra G, Stecca L, Tait S   +14 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A Web-Based Global Educational Model for Training in Semen Analysis during the COVID-19 Pandemic

The World Journal of Men's Health, 2021
Purpose: In response to the COVID-19 pandemic, the American Center for Reproductive Medicine (ACRM) transitioned its annual training in assisted reproductive technology (ART) from a hands-on, laboratory-based training course to a fully online training ...
Ashok Agarwal, Renata Finelli, Damayanthi Durairajanayagam, Kristian Leisegang, Rakesh Sharma, Sajal Gupta, Neha Singh, Andrea Belo, Mahsa Darbandi, Sarah Madani, Simryn Covarrubias, Sara Darbandi, Raha Sadeghi, Camila Pompeu, Florence Boitrelle, Hussein Kandil, Ramadan Saleh, Mohamed Arafa, Paraskevi Vogiatzi, Israel Maldonado Rosas, Christina Anagnostopoulou, Annapoorani Chockalingam, Kelly Athayde Wirka, Hassan N. Sallam, Rupin Shah, Ralf Henkel   +25 more
doaj   +1 more source

A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics

Frontiers in Endocrinology, 2023
BackgroundSemen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive.
Yi Guo, Jinli Li, Fengdan Hao, Yang Yang, Hao Yang, Qiurong Chang, Pengcheng Kong, Wenqiang Liu, Xianting Jiao, Xiaoming Teng   +9 more
doaj   +1 more source

PENGARUH FREKUENSI PENAMPUNGAN SEMEN TERHADAP KUALITAS SPERMATOZOA PADA AYAM BANGKOK [PDF]

, 2017
Penelitian ini bertujuan mengetahui pengaruh frekuensi penampungan semen terhadap kualitas spermatozoa ayam bangkok. Penelitian ini dilakukan di Laboratorium Reproduksi Fakultas Kedokteran Hewan Unsyiah pada bulan Desember 2015 sampai Januari 2016 ...
M Hijriyanto
core  

Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]

, 2018
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A., Antonini, G., Busetto, G. M., De Berardinis, E., Del Giudice, F., Gentile, V., Micic, S., Ragonesi, G., Virmani, A.   +8 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Effect of thyroxine replacement on leydig cell and sertoli cell function in men with hypothyroidism

Indian Journal of Endocrinology and Metabolism, 2020
Context: Thyroid hormones play an important role in reproductive and sexual function in both sexes. Comprehensive information on the ill-effects of hypothyroidism on Leydig cell, Sertoli cell and germ cell function is lacking in the existing literature ...
Jayakumar S Ambigapathy, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Ritesh Kumar, Nandhini Lakshmana Perumal   +4 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source