Results 31 to 40 of about 3,828,883 (311)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Dynamic simulation of semi-active suspension systems for durability analysis [PDF]

open access: yes, 2007
The benefits of vehicles with semi-active suspension systems have been widely accepted, mainly for improvement in ride and handling, over the passive system.
Ramli, Rahizar
core  

Optimal Design of Geared Joint for Semi-Active Knee Aid

open access: yesActuators
Knee flexion refers to the relative motion between the tibia and femur including rolling and sliding (rollback motion). Notwithstanding the individual variations in knee motion, conventional wearable knee-assistive devices use hinge joints—resulting in ...
Takehito Kikuchi   +3 more
doaj   +1 more source

Design of Solar Harvested Semi Active RFID Transponder with Supercapacitor Storage

open access: yesAdvances in Electrical and Electronic Engineering, 2015
This paper presents the analysis, design and manufacture of a low cost, low maintenance and long-range prototype of RFID transponder with continuous operability.
Gary Valentine   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Insights into the Active Sites and Kinetics of Double-site Catalysts for Semi-hydrogenation under Hydrogen Spillover

open access: yes, 2021
A well-defined catalyst with platinum (Pt) and gold (Au) encapsulated in micropore and mesopore of micro-mesoporous zeolite (TMSN), respectively, was designed to investigate the original active sites and kinetics of semi-hydrogenation.
Lv, Yipin   +7 more
core   +1 more source

A Semi‐active piezoelectric friction damper

open access: yesEarthquake Engineering & Structural Dynamics, 2014
SummaryThis research investigates the development of a semi‐active piezoelectric friction damper for controlling the seismic response of large‐scale structures. The proposed device is made of Duplex steel and leads to high friction capacity, which can be developed either in passive or semi‐active modes.
Pardo Varela Javier Ignacio   +1 more
openaire   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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