Results 11 to 20 of about 9,688 (167)

Single-Cell RNA Sequencing of Metastatic Testicular Seminoma Reveals the Cellular and Molecular Characteristics of Metastatic Cell Lineage

Frontiers in Oncology, 2022
BackgroundTesticular cancer is the most common solid malignancy in young men. Given the many histological classifications of testicular tumors, seminoma is one of the most treatable cancers.
Linjian Mo, Linjian Mo, Zhenyuan Yu, Zhenyuan Yu, Yufang Lv, Yufang Lv, Jiwen Cheng, Haibiao Yan, Wenhao Lu, Wenhao Lu, Cheng Su, Cheng Su, Qiang Ling, Qiang Ling, Zengnan Mo, Zengnan Mo   +15 more
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Anaplastic seminoma [PDF]

Cancer, 1977
Eight patients with the diagnosis of anaplastic seminoma of the testicle were treated during the megavoltage era from January 1959 to January 1976. Two patients with Stage I disease and one patient with Stage IV disease have died from their malignancy.
M, Kademian, A, Bosch, W L, Caldwell, W, Jaeschke   +3 more
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Late recurrence of Seminoma in the pelvis: A case report

Urology Case Reports, 2021
Recurrence of pure seminoma in atypical lymph node sites, such as the pelvis are rare masses that show clinical signs late in disease progression. We report a case of a 73-year-old male that presented with urinary retention and pain in his left lower ...
Seth Swinney, Allen Medway, Luis Brandi, Pranav Sharma   +3 more
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Baseline characteristics and patterns of care in testicular cancer patients: first data from the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS)

Swiss Medical Weekly, 2018
BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments.
Christian Rothermundt, Claudio Thurneysen, Richard Cathomas, Beat Müller, Walter Mingrone, Anita Hirschi-Blickenstorfer, Tobias Wehrhahn, Christian Ruf, Sacha I. Rothschild, Bettina Seifert, Angelika Terbuch, Thomas Grassmugg, Regina Woelky, Christian Fankhauser, Thomas Kunit, Natalie Fischer, Roman Inauen, Katrin Ziegler, Alan Haynes, Peter Jüni, Jeanine Kehl, Silke Gillessen   +21 more
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Three-gene prognostic biomarkers for seminoma identified by weighted gene co-expression network analysis.

PLoS ONE, 2020
Testicular germ cell tumors (TGCTs) are common in young males, and seminoma accounts for a large proportion of TGCTs. However, there are limited records on the exploration of novel biomarkers for seminoma.
Hualin Chen, Gang Chen, Yang Pan, Xiaoxiang Jin   +3 more
doaj   +1 more source

Spermatocytic Seminoma

Archives of Pathology & Laboratory Medicine, 2009
Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
openaire   +2 more sources

Clusterin suppresses invasion and metastasis of testicular seminoma by upregulating COL15a1

Molecular Therapy: Nucleic Acids, 2021
Seminoma is the most common subtype of testicular germ cell tumor, with an increasing incidence worldwide. Clusterin (CLU) expression was found to be downregulated in testicular seminoma in our previous study. We now expanded the sample size, and further
Yankang Cui, Chenkui Miao, Shouyong Liu, Jingyuan Tang, Jing Zhang, Hengtao Bu, Yuhao Wang, Chao Liang, Meiling Bao, Chao Hou, Jiajin Wu, Xiaochao Chen, Xiang Zhang, Zengjun Wang, Bianjiang Liu   +14 more
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Giant seminoma case with very small yolk sac and embryo carcinoma components, detected by intensive histopathological examination

Human Pathology: Case Reports, 2016
We experienced the giant seminoma with 18 × 10 × 10 cm sized and about 2.6 kg weight of 25 year old patient. We intensively examined the histological tissue type distributions in this giant seminoma. Most of the tumor consisted of seminoma components. In
Takeo Nakaya, MD, Shuichiro Kobayashi, MD, Satoshi Kitahara, MD, Akira Tanaka, MD, Hiroshi Kamma, MD, Akio Komatsu, MD   +5 more
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Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis

Cancer Informatics, 2022
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in adolescent and young men, with a rising incidence over the past 20 years.
Kirill E Medvedev, Anna V Savelyeva, Kenneth S Chen, Aditya Bagrodia, Liwei Jia, Nick V Grishin   +5 more
doaj   +1 more source

Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up

Cancer Imaging, 2022
Background Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not.
Ciara Conduit, Thuan Tzen Koh, Michael S Hofman, Guy C Toner, Jeremy Goad, Nathan Lawrentschuk, Keen-Hun Tai, Jeremy H Lewin, Ben Tran   +8 more
doaj   +1 more source