Results 21 to 30 of about 25,171 (251)
Late recurrence of Seminoma in the pelvis: A case report
Urology Case Reports, 2021 Recurrence of pure seminoma in atypical lymph node sites, such as the pelvis are rare masses that show clinical signs late in disease progression. We report a case of a 73-year-old male that presented with urinary retention and pain in his left lower ...
Seth Swinney +3 more
doaj +1 more source
Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results [PDF]
, 2016 Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after ...
De Felice, Francesca +4 more
core +2 more sources
Swiss Medical Weekly, 2018 BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments.
Christian Rothermundt +21 more
doaj +1 more source
Clusterin suppresses invasion and metastasis of testicular seminoma by upregulating COL15a1
Molecular Therapy: Nucleic Acids, 2021 Seminoma is the most common subtype of testicular germ cell tumor, with an increasing incidence worldwide. Clusterin (CLU) expression was found to be downregulated in testicular seminoma in our previous study. We now expanded the sample size, and further
Yankang Cui +14 more
doaj +1 more source
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. [PDF]
, 2015 Correct orientation of the mitotic spindle in stem cells underlies organogenesis. Spindle abnormalities correlate with cancer progression in germ line-derived tumors.
Bucko, Paula +8 more
core +1 more source
Archives of Pathology & Laboratory Medicine, 2009 Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
openaire +2 more sources
Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]
, 2000 Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core +1 more source
Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours. [PDF]
AndrologyAbstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Moody SC +6 more
europepmc +2 more sources
Transient increases in intracellular calcium and reactive oxygen species levels in TCam-2 cells exposed to microgravity [PDF]
, 2017 The effects of microgravity on functions of the human body are well described, including alterations in the male and female reproductive systems. In the present study, TCam-2 cells, which are considered a good model of mitotically active male germ cells,
Catizone, A +5 more
core +2 more sources
PLoS ONE, 2020 Testicular germ cell tumors (TGCTs) are common in young males, and seminoma accounts for a large proportion of TGCTs. However, there are limited records on the exploration of novel biomarkers for seminoma.
Hualin Chen +3 more
doaj +1 more source