Results 21 to 30 of about 33,270 (306)

Survival and New Prognosticators in Metastatic Seminoma: Results From the IGCCCG-Update Consortium

Journal of Clinical Oncology, 2021
PURPOSE The classification of the International Germ-Cell Cancer Collaborative Group (IGCCCG) has been a major advance in the management of germ-cell tumors, but relies on data of only 660 patients with seminoma treated between 1975 and 1990.
J. Beyer, L. Collette, N. Sauvé, G. Daugaard, D. Feldman, T. Tandstad, A. Tryakin, O. Ståhl, E. González-Billalabeitia, U. de Giorgi, S. Culine, R. de Wit, A. Hansen, Marko Bebek, A. Terbuch, C. Albany, M. Hentrich, J. Gietema, H. Negaard, R. Huddart, A. Lorch, F. Cafferty, D. Heng, C. Sweeney, E. Winquist, M. Chovanec, C. Fankhauser, D. Stark, P. Grimison, A. Necchi, B. Tran, A. Heidenreich, J. Shamash, C. Sternberg, D. Vaughn, I. Durán, C. Bokemeyer, A. Patrikidou, R. Cathomas, S. Assele, S. Gillessen   +40 more
semanticscholar   +1 more source

Metástase de seminoma em região orbital em cão - relato de caso [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
RESUMO O seminoma é uma neoformação testicular originária de células germinativas de ocorrência comum em cães, com maior prevalência em animais senis. Em geral, o comportamento biológico do seminoma canino é benigno.
S.L. Dias, L.R. Moroz, D.F.R.P. Souza, L.O. Simões, T.C. Peixoto, C.G. Pires   +5 more
doaj   +1 more source

Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment

Nature Communications, 2023
Seminoma is the most common malignant solid tumor in 14 to 44 year-old men. However, its molecular features and tumor microenvironment (TME) is largely unexplored.
Xiaojian Lu, Yanwei Luo, Xichen Nie, Bailing Zhang, Xiaoyan Wang, Ran Li, Guangmin Liu, Qianyin Zhou, Zhizhong Liu, Liqing Fan, James M. Hotaling, Zhe Zhang, Hao Bo, Jingtao Guo   +13 more
doaj   +1 more source

CHARACTERISTIC CHEMOTHERAPY RESPONSE OF TESTICULAR CANCER PATIENTS IN TERTIARY HOSPITAL

Jurnal Urologi Indonesia, 2022
Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution.
Dio Mafazi Fabrianta, Kurnia Penta Seputra, Besut Daryanto   +2 more
doaj   +1 more source

Serum Levels of MicroRNA-371a-3p (M371) Can Predict Absence or Presence of Vital Disease in Residual Masses After Chemotherapy of Metastatic Seminoma

Frontiers in Oncology, 2022
Background Radiological evaluation of postchemotherapy residual masses of metastatic seminoma is characterized by poor diagnostic accuracy. Serum levels of microRNA-371a-3p (M371) involve high specificity and sensitivity for the primary diagnosis of ...
K. Dieckmann, Markus Klemke, Francesca Grobelny, A. Radtke, Inken Dralle-Filiz, C. Wülfing, G. Belge   +6 more
semanticscholar   +1 more source

Thymic seminoma [PDF]

Indian Journal of Medical and Paediatric Oncology, 2009
AbstractThymic seminoma is a rare clinical entity. We report a case of an 18-year-old male patient who presented with chest pain, dyspnea, dysphagia of 1-month duration. Contrast-enhanced computer tomogram of chest showed an anterior mediastinal mass. He was subjected to thoracotomy and excision of the mass. Histopathology examination revealed seminoma
Kannan, J., Karkuzhali, P., Lakshminarasimhan, S.   +2 more
openaire   +2 more sources

The m6A methyltransferase METTL3 regulates autophagy and sensitivity to cisplatin by targeting ATG5 in seminoma

Translational Andrology and Urology, 2021
Background Our previous work shows Autophagy enhanced resistance to cisplatin in seminoma. The expression of the N6-methyladenosine (m6A) methyltransferases METTL3 was significantly increased in the cisplatin-resistant TCam-2 cell line of seminoma.
Hanfei Chen, Yali Xiang, Yinghao Yin, jingxuan peng, Dongyi Peng, Dongjie Li, R. Kitazawa, Yuxin Tang, Jianfu Yang   +8 more
semanticscholar   +1 more source

CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β

Acta Biochimica et Biophysica Sinica, 2022
Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to 35 years old. Although several molecular biomarkers have been identified to be associated with testicular seminoma pathogenesis, the exact ...
Cao Yuming, Chen Zhenlie, Qin Zihan, Qian Kaiyu, Liu Tongzu, Zhang Yuanzhen   +5 more
doaj   +1 more source

Baseline characteristics and patterns of care in testicular cancer patients: first data from the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS)

Swiss Medical Weekly, 2018
BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments.
Christian Rothermundt, Claudio Thurneysen, Richard Cathomas, Beat Müller, Walter Mingrone, Anita Hirschi-Blickenstorfer, Tobias Wehrhahn, Christian Ruf, Sacha I. Rothschild, Bettina Seifert, Angelika Terbuch, Thomas Grassmugg, Regina Woelky, Christian Fankhauser, Thomas Kunit, Natalie Fischer, Roman Inauen, Katrin Ziegler, Alan Haynes, Peter Jüni, Jeanine Kehl, Silke Gillessen   +21 more
doaj   +1 more source

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results [PDF]

, 2016
Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after ...
De Felice, Francesca, Gravina, Giovanni Luca, Marampon, Francesco, Musio, Daniela, Tombolini, Vincenzo   +4 more
core   +2 more sources