Results 91 to 100 of about 2,737,612 (273)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

VS-GRU: A Variable Sensitive Gated Recurrent Neural Network for Multivariate Time Series with Massive Missing Values

Applied Sciences, 2019
Multivariate time series are often accompanied with missing values, especially in clinical time series, which usually contain more than 80% of missing data, and the missing rates between different variables vary widely. However, few studies address these
Qianting Li, Yong Xu
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Measuring Sensitive Personality and its Relationship to some Variables among Workers in Care Institutions for People with Special Needs in the Kurdistan Region of Iraq

مجلة كلية التربية للبنات
The current research aims to build a measure of the sensitive personality among those working with people with special needs, and then identify the statistical significance of the differences in the level of sensitive personality among those working ...
Vaman Ahmad Mohammed, Sabir Saeed Abdullah   +1 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Estimation of Population Variance for a Sensitive Variable in Stratified Sampling Using Randomized Response Technique

Revstat Statistical Journal
In this paper, Randomized Response technique (RRT) is used to propose some separate and combined variance estimators for a sensitive variable using stratified random sampling.
Badr Aloraini, Sadia Khalil, Muhammad Nouman Qureshi, Sat Gupta   +3 more
doaj   +1 more source

Grouping & regrouping using Mixintools: An exploratory study [PDF]

, 2008
On a regular basis, teachers find it necessary to place children into groups for instruction. Random assignment is typically the norm when group composition is immaterial to the task.
Berlach, Richard G, McNaught, Keith
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source