Results 41 to 50 of about 98,133 (220)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The Dynamic Characteristic of a Faulted Rotor System with Multi-Objective Optimization Designed SFD

Applied Sciences, 2019
As an important part of the turbomachinery, the rotor–bearing system has been upgraded to provide a high rotating speed in order to meet the demand of high power production.
Liang Ma, Jun Wang, Guichang Zhang
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Machine learning-driven building energy optimization: integrating EnsembleXGBoost sensitivity analysis with meta-heuristic algorithms and carbon economics

Energy Conversion and Management: X
While recent building optimization studies achieve significant energy reductions, they often overlook two critical gaps: (1) proceeding on fixed, non-optimized building geometries, and (2) using machine learning (ML) solely as computational surrogates ...
Mahdi Asghari, Melika Jahangiri, Khosro Ashrafi   +2 more
doaj   +1 more source

Second-order subdifferential calculus with applications to tilt stability in optimization [PDF]

, 2011
The paper concerns the second-order generalized differentiation theory of variational analysis and new applications of this theory to some problems of constrained optimization in finitedimensional spaces. The main attention is paid to the so-called (full
Mordukhovich, B. S., Rockafellar, R. T.
core   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Impact Analysis of Hull Line Design on Fishing Vessels’ Vulnerability to Pure Loss of Stability

Journal of Marine Science and Engineering
Pure Loss of Stability is one of the five typical stability failure modes identified in the Second-Generation Intact Stability Criteria by the IMO. This study investigates the influence of hull line variations on the vulnerability of a saury fishing ...
Hangming Zhang, Kai Li, Guoxiong Mei, Jianzhao Ding, Qiqi Wu   +4 more
doaj   +1 more source

On the Selection of Tuning Methodology of FOPID Controllers for the Control of Higher Order Processes [PDF]

, 2012
In this paper, a comparative study is done on the time and frequency domain tuning strategies for fractional order (FO) PID controllers to handle higher order processes. A new fractional order template for reduced parameter modeling of stable minimum/non-
Alomoush, Amitava Gupta, Astrom, Astrom, Astrom, Bettou, Bhambhani, Biswas, Biswas, Bohannan, Bouafoura, Cao, Caponetto, Caponetto, Castillo, Chao, Charef, Chen, Chen, Das, Dorcak, Dwyer, Hamamci, Hamamci, Ho, Isaksson, Lanusse, Lee, Li, Luo, Luo, Malwatkar, Martin, Merrikh-Bayat, Monje, Monje, Nelder, Oustaloup, Oustaloup, Oustaloup, Padula, Panagopoulos, Petras, Podlubny, Podlubny, Saha, Saha, Saleh Tavazoei, Santamaria, Saptarshi Das, Seborg, Shantanu Das, Shen, Suman Saha, Valerio, Zamani, Zhuang   +56 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

UNCERTAIN MODEL OF REACTOR IN PROCESS OF PRODUCTION GREASE ON SOAP THICKENERS

Вісник Національного технічного університету України «Київський політехнічний інститут імені Ігоря Сікорського»: Серія «Хімічна інженерія, екологія та ресурсозбереження», 2017
In this article consider the problem of guaranteed quality controlled processes with uncertain parameters of the functional components of management, set interval or fuzzy way.
Антон Петрович Коротинський, Михайло Володимирович Коржик   +1 more
doaj   +1 more source