Results 71 to 80 of about 3,413,860 (319)
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Journal of Marine Science and Engineering, 2020 In this paper, we report on the characterization of the sensitivity and the directionality of a novel ultrasonic hydrophone fabricated by micro-electro-mechanical systems (MEMS) process, using aluminum nitride (AlN) thin film as piezoelectric functional ...
Basit Abdul +6 more
doaj +1 more source
Fast protection scheme for flexible DC transmission line based on voltage traveling wave steepness
电力工程技术, 2023 Flexible DC technology has revolutionary significance in flexibly solving the problem of high proportion of new energy consumption. Due to the vulnerability of high-ratio power electronic equipment and the difficulty in extracting fault information ...
GAO Zhengchuang +3 more
doaj +1 more source
Synthese, 2010 In this paper, I argue that there are good motivations for a relativist account of the domain-sensitivity of quantifier phrases. I will frame the problem as a puzzle involving what looks like a logically valid inference, yet one whose premises are true while the conclusion is false. After discussing some existing accounts, literalist and contextualist,
openaire +3 more sources
Clinical Nephrology, 2004 Lithium is still the treatment of choice in bipolar affective disorder. The patient presented here represents an example of the possible severity of metabolic defects resulting from lithium use. In this case, it caused severe intractable nephrogenic diabetes insipidus (NDI). Our case report draws attention to 2 important messages.
Ashrafian, H, Bogle, R
openaire +4 more sources
On Block Sensitivity and Fractional Block Sensitivity [PDF]
Lobachevskii Journal of Mathematics, 2018 We investigate the relation between the block sensitivity $\text{bs}(f)$ and fractional block sensitivity $\text{fbs}(f)$ complexity measures of Boolean functions. While it is known that $\text{fbs}(f) = O(\text{bs}(f)^2)$, the best known separation achieves $\text{fbs}(f) = \left(\frac{1}{3\sqrt2} +o(1)\right) \text{bs(f)}^{3/2}$.
Jevgēnijs Vihrovs +2 more
openaire +3 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source