Results 71 to 80 of about 10,108,798 (388)
, 1999 VERITAS is a new major ground-based gamma-ray observatory with an array of seven 10 m optical reflectors to be built at the Whipple Observatory in southern Arizona, USA.
Barrio +7 more
core +2 more sources
Higher-order knowledge and sensitivity [PDF]
, 2020 It has recently been argued that a sensitivity theory of knowledge cannot account for intuitively appealing instances of higher-order knowledge. In this paper, we argue that it can once careful attention is paid to the methods or processes by which we ...
Bjerring, Jens Christian +1 more
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Frontiers in Molecular Biosciences, 2019 Nuclear magnetic resonance (NMR) spectroscopy is widely used as a metabolomics tool, and 1D spectroscopy is overwhelmingly the commonest approach. The use of 2D spectroscopy could offer significant advantages in terms of increased spectral dispersion of ...
Florian M. Geier +2 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Loci specific epigenetic drug sensitivity. [PDF]
, 2020 Therapeutic targeting of epigenetic modulators offers a novel approach to the treatment of multiple diseases. The cellular consequences of chemical compounds that target epigenetic regulators (epi-drugs) are complex.
Pilko, Anna +2 more
core +1 more source
Jurnal Penelitian Fisika dan Aplikasinya, 2019 Sensitivity is the comparison result between changes in output signal intensity and changes in input signal shift sensor. The purpose of this study was to analyze the sensitivity of fiber optic sensors using mathematical analysis through the Gaussian ...
Mohammad Budiyanto +2 more
doaj +1 more source
Epidemiology, 2016 Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the increasing size and coverage of genome-wide association studies and the increasing availability of summarized data on genetic associations with risk ...
S. Burgess +4 more
semanticscholar +1 more source
Synthese, 2010 In this paper, I argue that there are good motivations for a relativist account of the domain-sensitivity of quantifier phrases. I will frame the problem as a puzzle involving what looks like a logically valid inference, yet one whose premises are true while the conclusion is false. After discussing some existing accounts, literalist and contextualist,
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source