Results 121 to 130 of about 2,595,666 (406)

A Sensitive and Specific Bioassay for Oxytocin

open access: yesExperimental Biology and Medicine, 1970
SummaryA method for quantitative assay of oxytocin using strips from the mammary gland of lactating mice has been studied. The method is suitable for determinations of small amounts of oxytocin. Doses as small as 10 μU/ml can be estimated. The precision of the method is high and it is highly specific.
S. Melander   +6 more
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Are you suffering from a large arterial occlusion? Please raise your arm! [PDF]

open access: yes, 2018
Background and purpose: Triage tools to identify candidates for thrombectomy are of utmost importance in acute stroke. No prognostic tool has yet gained any widespread use.
Abdul-Rahim, Azmil H.   +11 more
core   +1 more source

The sensitivity, specificity, predictive values, and likelihood ratios of fecal occult blood test for the detection of colorectal cancer in hospital settings

open access: yesClinical and Experimental Gastroenterology, 2015
Salah H Elsafi,1 Norah I Alqahtani,1 Nawaf Y Zakary,2 Eidan M Al Zahrani,3 1Clinical Laboratory Science Department, Prince Sultan Military College of Health Sciences, Dhahran, 2Gastroenterology and Endoscopy Unit, Internal Medicine Department, King Fahd ...
Elsafi SH   +3 more
doaj  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Microfluidic method for rapid turbidimetric detection of the DNA of Mycobacterium tuberculosis using loop-mediated isothermal amplification in capillary tubes [PDF]

open access: yes, 2015
We describe a microfluidic method for rapid isothermal turbidimetric detection of the DNA of Mycobacterium tuberculosis. Loop-mediated isothermal amplification is accomplished in capillary tubes for amplifying DNA in less than 15 min, and sensitivity and
Gill, P., Rafati, A.
core  

Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]

open access: yes, 2014
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K   +8 more
core   +1 more source

Proper Estimation of Sensitivity and Specificity [PDF]

open access: yesClinical and Vaccine Immunology, 2006
I write to express concern about the diagnostic accuracy statements of Eda et. al. concerning a new Johne's disease enzyme-linked immunosorbent assay (ELISA) (2). The diagnostic sensitivity of this new ELISA for bovine paratuberculosis, reported to be 100%, was based on only 64 (according to the Materials and Methods) or 51 (according to the Results)
openaire   +3 more sources

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