Results 71 to 80 of about 4,361,080 (379)

Grader agreement, and sensitivity and specificity of digital photography in a community optometry-based diabetic eye screening program

Clinical Ophthalmology, 2014
Luckni Sellahewa,1,2 Craig Simpson,2 Prema Maharajan,2 John Duffy,2 Iskandar Idris3 1Diabetic Medicine Department, Nottingham University Hospitals, 2North Nottinghamshire Eye Screening Service, Sherwood Forest Hospitals Foundation Trust, 3Division of ...
Sellahewa L, Simpson C, Maharajan P, Duffy J, Idris I   +4 more
doaj  

Performance of a rapid diagnostic test for the detection of visceral leishmaniasis in a large urban setting

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction Rapid diagnostic tests (RDTs) may improve the early detection of visceral leishmaniasis (VL), but their real-world performance requires additional study.
Alexandre Sampaio Moura, Helen Maria Ramos de Oliveira Lopes, Maria Vitoria Assumpcao Mourao, Maria Helena Franco Morais   +3 more
doaj   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Sensitivity analysis for publication bias on the time-dependent summary ROC analysis in meta-analysis of prognosis studies [PDF]

arXiv, 2023
In the analysis of prognosis studies with time-to-event outcomes, dichotomization of patients is often made. As the evaluations of prognostic capacity, the survivals of groups with high/low expression of the biomarker are often estimated by the Kaplan-Meier method, and the difference between groups is summarized via the hazard ratio (HR).
arxiv  

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Evaluation of updated sepsis scoring systems and systemic inflammatory response syndrome criteria and their association with sepsis in equine neonates [PDF]

, 2018
BackgroundThe original equine sepsis score provided a method of identifying foals with sepsis. New variables associated with sepsis have been evaluated, but the sepsis score has not been updated.ObjectivesTo evaluate the sensitivity and specificity of 2 ...
Bates, Bone, Bone, Book, Borchers, Borchers, Brewer, Brewer, Castagnetti, Cohen, Corley, Corley, Dellinger, Dembek, Giguere, Goldstein, Hackett, Hanley, Hollis, Hytychová, Jaimes, Marsh, Muckart, Pusterla, Rangel-Frausto, Rohrbach, Russell, Singer, Toth, Troger, Venkatesh, Vincent, Weber, Weinstein, Wilson, Wong, Zabrecky   +36 more
core   +1 more source

Screening Characteristics of Ultrasonography in Detection of Ankle Fractures

Archives of Academic Emergency Medicine, 2018
Introduction: Ankle fracture is one of the most common joint fractures. X-ray and physical examination are its main methods of diagnosis. Recently, ultrasonography (US) is considered as a simple and non-invasive method of fracture diagnosis.
Majid Shojaee, Farhad Hakimzadeh, Parisa Mohammadi, Anita Sabzghabaei, Mohammad Manouchehrifar, Ali Arhami Dolatabadi   +5 more
doaj   +1 more source

Sensitivity and specificity of using exercise heart rate in a thermoneutral environment to predict heat tolerance status

International Journal of Occupational Medicine and Environmental Health, 2023
Objectives Following heat illness, a return to activity may require passing a heat tolerance test (HTT). However, there are several logistical limitations to the widespread use of the HTT.
Sarah Northway, Douglas Jones, Michael Buono   +2 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Measurements of complement factor H-related protein (BTA-TRAK (TM) assay) and nuclear matrix protein (NMP22 assay) - Useful diagnostic tools in the diagnosis of urinary bladder cancer? [PDF]

, 2003
Between 1997 and 2000 we investigated in a prospective study the voided urine samples of all consecutive patients undergoing cystoscopy independent from their clinical background (n=705) with the BTA-TRAK(TM) assay (Bard Diagnostics, Redmont, USA ...
Hofmann, Karin, Holdenrieder, Stefan, Kriegmair, Martin, Mahnert, Brigitte, Nagel, Dorothea, Reiter, Wolfgang, Schmeller, Nikolaus, Stieber, Petra, Tauber, Stephan   +8 more
core   +1 more source