Results 71 to 80 of about 4,475,159 (380)

Physical Examination of the Ankle: A Review of the Original Orthopedic Special Test Description and Scientific Validity of Common Tests for Ankle Examination

Archives of Rehabilitation Research and Clinical Translation, 2020
Objectives: To review the literature, identify and describe commonly used special tests for diagnosing injury to the ligaments of the ankle complex, present the distinguishing characteristics and limitations of each test, and discuss the current evidence
Lindsay W. Larkins, DAT, Russell T. Baker, PhD, DAT, Jayme G. Baker, DPT   +2 more
doaj  

Sensitivity and specificity of diagnostic tests for Lassa fever: a systematic review. [PDF]

, 2019
BACKGROUND: Lassa fever virus has been enlisted as a priority pathogen of epidemic potential by the World Health organization Research and Development (WHO R & D) Blueprint. Diagnostics play a crucial role in epidemic preparedness. This systematic review
Brangel, Polina, Peeling, Rosanna, Shrestha, Priyanka, Takah, Noah Fongwen   +3 more
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Performance of a rapid diagnostic test for the detection of visceral leishmaniasis in a large urban setting

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction Rapid diagnostic tests (RDTs) may improve the early detection of visceral leishmaniasis (VL), but their real-world performance requires additional study.
Alexandre Sampaio Moura, Helen Maria Ramos de Oliveira Lopes, Maria Vitoria Assumpcao Mourao, Maria Helena Franco Morais   +3 more
doaj   +1 more source

Sensitivity analysis for publication bias on the time-dependent summary ROC analysis in meta-analysis of prognosis studies [PDF]

arXiv, 2023
In the analysis of prognosis studies with time-to-event outcomes, dichotomization of patients is often made. As the evaluations of prognostic capacity, the survivals of groups with high/low expression of the biomarker are often estimated by the Kaplan-Meier method, and the difference between groups is summarized via the hazard ratio (HR).
arxiv  

Evaluation of updated sepsis scoring systems and systemic inflammatory response syndrome criteria and their association with sepsis in equine neonates [PDF]

, 2018
BackgroundThe original equine sepsis score provided a method of identifying foals with sepsis. New variables associated with sepsis have been evaluated, but the sepsis score has not been updated.ObjectivesTo evaluate the sensitivity and specificity of 2 ...
Bates, Bone, Bone, Book, Borchers, Borchers, Brewer, Brewer, Castagnetti, Cohen, Corley, Corley, Dellinger, Dembek, Giguere, Goldstein, Hackett, Hanley, Hollis, Hytychová, Jaimes, Marsh, Muckart, Pusterla, Rangel-Frausto, Rohrbach, Russell, Singer, Toth, Troger, Venkatesh, Vincent, Weber, Weinstein, Wilson, Wong, Zabrecky   +36 more
core   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

FEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet, Magali Leroy, Alexandre Maes, Ciarán Condon, Frédérique Braun   +4 more
wiley   +1 more source

Grader agreement, and sensitivity and specificity of digital photography in a community optometry-based diabetic eye screening program

Clinical Ophthalmology, 2014
Luckni Sellahewa,1,2 Craig Simpson,2 Prema Maharajan,2 John Duffy,2 Iskandar Idris3 1Diabetic Medicine Department, Nottingham University Hospitals, 2North Nottinghamshire Eye Screening Service, Sherwood Forest Hospitals Foundation Trust, 3Division of ...
Sellahewa L, Simpson C, Maharajan P, Duffy J, Idris I   +4 more
doaj  

Sensitivity and specificity of detection methods for erythropoietin doping in cyclists [PDF]

, 2019
Recombinant human erythropoietin (rHuEPO) is used as doping a substance. Anti-doping efforts include urine and blood testing and monitoring the athlete biological passport (ABP).
Burggraaf, Jacobus, Cohen, Adam F, Daniels, Johannes MA, Gal, Pim, Heuberger, Jules AAC, Hon, Olivier, Post, Titiaan E, Ram, Herman, Rotmans, Joris I, Stuurman, Frederik E, Van Eenoo, Peter   +10 more
core   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source