Results 81 to 90 of about 764,096 (293)
Sensitivity Analysis of Compressive Sensing Solutions
Frontiers in Robotics and AI, 2015 The compressive sensing framework □nds a wide range of applications in signal processing, data analysis and fusion. Within this framework, various methods have been proposed to □nd a sparse solution x from a linear measurement model y = Ax.
Liyi eDai
doaj +1 more source
Robust Prediction of Anti-Cancer Drug Sensitivity and Sensitivity-Specific Biomarker
PLoS ONE, 2014 The personal genomics era has attracted a large amount of attention for anti-cancer therapy by patient-specific analysis. Patient-specific analysis enables discovery of individual genomic characteristics for each patient, and thus we can effectively predict individual genetic risk of disease and perform personalized anti-cancer therapy.
Heewon Park +3 more
openaire +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
IEEE Photonics Journal, 2017 Low current sensitivity and insufficient system robustness are two significant obstacles preventing widespread use of all-fiber current sensors (AFCSs). We demonstrate a novel AFCS combining a fiber-loop architecture and a reflection scheme.
Hao Zhang
doaj +1 more source
, 2008 We investigate the robustness with respect to nonconformality of five properties of strongly coupled plasmas that have been calculated in N=4 supersymmetric Yang-Mills (SYM) theory at nonzero temperature, motivated by the goal of understanding phenomena ...
Liu, Hong +2 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness. [PDF]
Proc Natl Acad Sci U S A, 2022 Hernando-Amado S +3 more
europepmc +1 more source
Sensitivity of Inequality Measures to Extreme Values [PDF]
We examine the sensitivity of estimates and inequality indices to extreme values, in the sense of their robustness properties and of their statistical performance.
Emmanuel Flachaire, Frank A Cowell
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source