Results 151 to 160 of about 2,274,512 (358)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Investigation into a new denervation model of the sciatic nerve zones in rats: Selective motor or sensorial denervation

Objective: This study aimed to introduce a reliable and useful model of selective sensorial or motor denervations of the sciatic nerve in rats with clinical and laboratory outcomes. Methods: The surgical technique was determined via detailed cadaveric
Fuat Uslusoy, Mustafa Asım Aydın, Levent Sarikcioglu, Hasan Rifat Koyuncuoğlu, İbrahim Metin Çiriş, Osman Gurdal, Selman Hakkı Altuntaş   +6 more
core   +1 more source

Integración sensorial [PDF]

, 2007
Presentación que facilita el estudio sobre la integración ...
Suárez Figueroa, Milena
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The Effect of Process Parameters on the Microstructure, Stability, and Sensorial Properties of an Emulsion Cream Formulation

Pharmaceutics
A classical emulsion formulation based on petrolatum and mineral oil as the internal phase with emulsifier wax as a typical topical emulsion cream was investigated for the effect of process parameters on drug product quality and performance attributes ...
Pui Shan Chow, Ron Tau Yee Lim, Febin Cyriac, Jaymin C. Shah, Abu Zayed Md Badruddoza, Thean Yeoh, Chetan Kantilal Yagnik, Xin Yi Tee, Annie Bao Hua Wong, Vernissa Dilys Chia, Guan Wang   +10 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Produção de blends a partir de frutos tropicais e nativos da Amazônia Production of blends based on tropical and native fruits from brazilian Amazon

Revista Brasileira de Fruticultura, 2011
Neste trabalho, objetivou-se o enriquecimento nutricional de néctares de frutos, pelo processamento de blends, usando-se fruteiras tropicais e Amazônicas produzidas em Roraima.
Leandro Camargo Neves, Ronaldo Moreno Benedette, Jéssica Milanez Tosin, Edvan Alves Chagas, Vanuza Xavier da Silva, Marcos André de Souza Prill, Sergio Ruffo Roberto   +6 more
doaj  

Sensory and chemical evaluation of tea brews prepared with the assistance of ultrasound

Ciência Rural
: The aim of the study was to evaluate sensory and phytochemical (polyphenols, flavonoids and caffeine) estimation of black and green tea brews obtained in an alternative way through brewing with the assistance of ultrasound.
Radosław Kowalski, Jakub Wyrostek, Klaudia Kałwa, Grażyna Kowalska, Urszula Pankiewicz, Monika Sujka, Marzena Włodarczyk-Stasiak, Artur Mazurek   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Sistema sensorial inteligente com tecnologia de comunicações wireless

, 2007
Mestrado em Física AplicadaApresenta-se um sistema sensorial inteligente com comunicação de dados wireless, usando o protocolo de comunicações Bluetooth, com uma interface analógica-digital para sinais de baixa frequência e de baixo custo, baseada na ...
Correia, Alexandre Manuel Ribeiro
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