Results 71 to 80 of about 6,354,722 (247)

Learning in a changing environment [PDF]

, 2009
Multiple cue probability learning studies have typically focused on stationary environments. We present three experiments investigating learning in changing environments.
Shanks, D.R., Speekenbrink, M.
core  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

A subcortical circuit linking the cerebellum to the basal ganglia engaged in vocal learning

eLife, 2018
Speech is a complex sensorimotor skill, and vocal learning involves both the basal ganglia and the cerebellum. These subcortical structures interact indirectly through their respective loops with thalamo-cortical and brainstem networks, and directly via ...
Ludivine Pidoux, Pascale Le Blanc, Carole Levenes, Arthur Leblois   +3 more
doaj   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

A safe reinforcement learning approach for autonomous navigation of mobile robots in dynamic environments

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract When deploying mobile robots in real‐world scenarios, such as airports, train stations, hospitals, and schools, collisions with pedestrians are intolerable and catastrophic. Motion safety becomes one of the most fundamental requirements for mobile robots.
Zhiqian Zhou, Junkai Ren, Zhiwen Zeng, Junhao Xiao, Xinglong Zhang, Xian Guo, Zongtan Zhou, Huimin Lu   +7 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Contextual Interference Effect Is Independent of Retroactive Inhibition but Variable Practice Is Not Always Beneficial

Frontiers in Human Neuroscience, 2019
Positive effects of variable practice conditions on subsequent motor memory consolidation and generalization are widely accepted and described as the contextual interference effect (CIE).
Benjamin Thürer, Benjamin Thürer, Sarah Gedemer, Anne Focke, Thorsten Stein   +4 more
doaj   +1 more source

Regaining Motor Control in Musician's Dystonia by Restoring Sensorimotor Organization [PDF]

, 2009
Professional musicians are an excellent human model of long term effects of skilled motor training on the structure and function of the motor system.
Rosenkranz, K., Williamon, A., Williamon, A, Rothwell, JC, Rosenkranz, K, Butler, K., Rothwell, J. C., Butler, K   +7 more
core   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Quantifying exploration in reward-based motor learning

, 2020
Exploration in reward-based motor learning is observable in experimental data as increased variability. In order to quantify exploration, we compare three methods for estimating other sources of variability: Sensorimotor noise.
Van Mastrigt, Nina M., Smeets, Jeroen B.J., Nina M van Mastrigt, Van Der Kooij, Katinka; id_orcid, Katinka van der Kooij, Van Mastrigt, Nina M.; id_orcid, Jeroen B J Smeets, Smeets, Jeroen B.J.; id_orcid, Van Der Kooij, Katinka   +8 more
core   +1 more source