Results 91 to 100 of about 389,530 (297)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Televizyon Haberlerinde Erişilebilirlik Üzerine Bazı Gözlem ve Öneriler
Selçuk İletişim, 2020 Bu çalışmada televizyon haberlerinin duyusal engeli olan izleyiciler açısından erişilebilirlik düzeyi ele alınmıştır. 15 farklı kanala ait 20 haberden oluşan örneklem, nitel yöntemle çözümlenerek erişilebilirliğin görsel ve işitsel iletişim kanallarından
Mine Güven
doaj
Interventions for improving upper limb function after stroke [PDF]
, 2013 Background: Improving upper limb function is a core element of stroke rehabilitation needed to maximise patient outcomes and reduce disability. Evidence about effects of individual treatment techniques and modalities is synthesised within many reviews ...
Brady, Marian C. +6 more
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
BMC GeriatricsBackground Few studies have examined sensory impairment (visual and auditory) as a risk factor for cognitive impairment in older people living in nursing homes. This study analysed the combined effect of visual and auditory impairment (dual sensory loss)
Covadonga Vázquez-Sánchez +2 more
doaj +1 more source
Sensory Impairments among Canadians 55 years and Older: An Analysis of 1986 and 1991 Health and Activity Limitation Survey [PDF]
It has been well established that increasing age is associated with worsening health and decreasing functional ability among seniors, including conditions that lead to hearing and seeing impairments.
Joan Lindsay +3 more
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Whiplash: the possible impact of context on diagnosis [PDF]
, 2015 This study explores the importance of context when diagnosing Whiplash Associated Disorders (WAD). Whiplash is a complex injury and there is considerable variation in its diagnosis and treatment.
Earle, Fiona, Flynn, J M, Horne, Joanna
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Investigation of the Functional Balance in Children With Sensory Impairment Aged 6 to 14 Years Old
Biyumikānīk-i varzishī, 2020 Objective: The balance of human body is maintained by a complex process involving visual, vestibular, and proprioceptive systems. Since the postural control require information from all of these three sensory systems to maintain optimal postural ...
Hassan Daneshmandi, Chiman َAlyarnezhad
doaj
Follow-up study of sensory-motor polyneuropathy in Type 1 (insulin-dependent) diabetic subjects after simultaneous pancreas and kidney transplantation and after graft rejection [PDF]
, 1991 The influence of successful simultaneous pancreas and kidney transplantation on peripheral polyneuropathy was investigated in 53 patients for a mean observation period of 40.3 months. Seventeen patients were followed-up for more than 3 years.
A. Abendroth +16 more
core +1 more source