Results 81 to 90 of about 389,530 (297)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Sensory Impairment and Health-Related Quality of Life

open access: yesIranian Journal of Public Health, 2015
Background: Sensory impairment is a common condition that exerts negative effects on health-related quality of life (HRQoL) in the elderly. This study aimed to determine the relationship between sensory impairment and HRQoL and identify sensory-specific ...
Hye-Jin KWON   +4 more
doaj  

A Guide to Disability Statistics from the 2000 Decennial Census [PDF]

open access: yes, 2005
This User Guide addresses disability data available in the 2000 Decennial Census. A decennial census of the United States is conducted every ten years to provide statistics at the national, state, and local levels. The short form of the decennial census
Erickson, William   +1 more
core   +1 more source

Causal contribution and dynamical encoding in the striatum during evidence accumulation. [PDF]

open access: yes, 2018
A broad range of decision-making processes involve gradual accumulation of evidence over time, but the neural circuits responsible for this computation are not yet established.
Brody, Carlos D   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Motor and sensory impairment in survivors of childhood central nervous system (CNS) tumors in the St. Jude Lifetime Cohort (SJLIFE)

open access: yesCancer Medicine
Background Survivors of childhood central nervous system (CNS) tumors can develop motor and sensory impairment from their cancer and treatment history.
Rozalyn L. Rodwin   +16 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sensory impairment reduces money sharing in the Dictator Game regardless of the recipient's sensory status.

open access: yesPLoS ONE, 2020
Altruism varies as a function of minimal social cues. Sensory impaired individuals elicit more altruistic behaviors, at the same time being more prone to be exploited.
Anna Oleszkiewicz, Teresa Kupczyk
doaj   +1 more source

Trunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial. [PDF]

open access: yes, 2018
BACKGROUND: Virtual reality and augmented feedback have become more prevalent as training methods to improve balance. Few reports exist on the benefits of providing trunk motion visual feedback (VFB) during treadmill walking, and most of those reports ...
Anson, Eric   +6 more
core   +1 more source

Submovements During Reaching Movements after Stroke [PDF]

open access: yes, 2014
Neurological deficits after cerebrovascular accidents very frequently disrupt the kinematics of voluntary movements with the consequent impact in daily life activities.
Ghez, Claude   +4 more
core   +2 more sources

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