Results 71 to 80 of about 1,534,956 (198)

Activation of TRPV4 regulates respiration through indirect activation of bronchopulmonary sensory neurons

Frontiers in Physiology, 2016
Transient receptor potential vanilloid receptor 4 (TRPV4) is a calcium-permeable non-selective cation channel implicated in numerous physiological and pathological functions.
Qihai (David) eGu, Charles R. Moss, Kristen L. Kettelhut, Carolyn A. Gilbert, Hongzhen eHu   +4 more
doaj   +1 more source

IL-33/ST2 drives inflammatory pain via CCL2 signaling and activation of TRPV1 and TRPM8

Communications Biology
Innate immunity is the first line of host defense and contributes to pain. However, how innate immune system interacts with sensory neurons to govern pain remains poorly understood.
Linjie Wang, Jingyun Zhang, Shijuan Qiu, Ruizhen Huang, Yuge Wang, Yuting Wang, Mingyu Li, Qingqing Ye, Sibo Zhang, Zhenhua Qi, Lan Cao, Guohao Li, Yajie An, Denghui Xie, Wenli Mi, Huaqiao Wang, Tao Luo, Jingdun Xie, Junting Huang   +18 more
doaj   +1 more source

Purinergic receptor antagonists inhibit odorant-mediated CREB phosphorylation in sustentacular cells of mouse olfactory epithelium

BMC Neuroscience, 2011
Background Extracellular nucleotides have long been known to play neuromodulatory roles and to be involved in intercellular signalling. In the olfactory system, ATP is released by olfactory neurons, and exogenous ATP can evoke an increase in ...
Hatt Hanns, Toetter Bastian, Mashukova Anastasia, Dooley Ruth, Neuhaus Eva M   +4 more
doaj   +1 more source

Subcellular localization of the P2X4 receptor in sensory hair cells of Wistar rat cochlea

Histochemistry and Cell Biology
Abstract Our sense of hearing starts in the inner ear organ, the cochlea, which contains two types of auditory hair cells for signal transduction. Earlier research showed that the complex cochlear physiology is regulated in part by purinergic signalling through activation of purine-mediated P2X, P2Y and adenosine receptors expressed ...
Huang, Ziyin, Ross, Jacqueline M., Lin, Shelly C. Y., Kumar, Prakansha N., Roy, Kevin, Vlajkovic, Srdjan M., Thorne, Peter R., Suzuki-Kerr, Haruna   +7 more
openaire   +2 more sources

Sema7A/PlxnCl signaling triggers activity-dependent olfactory synapse formation

Nature Communications, 2018
The molecular mechanisms underlying synapse formation in the olfactory bulb are not fully understood. Here the authors demonstrate that semaphorin 7A on olfactory sensory neurons, and its receptor plexin C1 expressed on mitral and tufted cells, is ...
Nobuko Inoue, Hirofumi Nishizumi, Hiromi Naritsuka, Hiroshi Kiyonari, Hitoshi Sakano   +4 more
doaj   +1 more source

Drosophila HCN mediates gustatory homeostasis by preserving sensillar transepithelial potential in sweet environments

eLife
Establishing transepithelial ion disparities is crucial for sensory functions in animals. In insect sensory organs called sensilla, a transepithelial potential, known as the sensillum potential (SP), arises through active ion transport across accessory ...
MinHyuk Lee, Se Hoon Park, Kyeung Min Joo, Jae Young Kwon, Kyung-Hoon Lee, KyeongJin Kang   +5 more
doaj   +1 more source

The Evolution of Sensory Placodes

The Scientific World Journal, 2006
The vertebrate cranial sensory placodes are ectodermal embryonic patches that give rise to sensory receptor cells of the peripheral paired sense organs and to neurons in the cranial sensory ganglia.
Francoise Mazet
doaj   +1 more source

Subcellular Localization of the P2X4 Receptor in Cochlear Sensory Hair Cells

Abstract Our sense of hearing starts in the inner ear organ, the cochlea, which contains two types of auditory hair cells for signal transduction. Earlier research showed that the complex cochlear physiology is regulated in part by purinergic signalling through activations of purine mediated P2X, P2Y and adenosine receptors expressed in the ...
Ziyin Silver Huang, Jacqueline M Ross, Shelly CY Lin, Kevin Roy, Srdjan M Vlajkovic, Peter R. Thorne, Haruna Suzuki-Kerr   +6 more
openaire   +1 more source

How Foraging Mode Sculpts Sensory Systems: Morphological Evidence From DiceCT and Histology in Sympatric Lizards

Ecology and Evolution
The relationship between foraging modes and sensory system morphology is critical for understanding the ecological and evolutionary adaptations of lizards.
Lin Leng, Lei Shi
doaj   +1 more source

G protein-coupled receptor-based thermosensation determines temperature acclimatization of Caenorhabditis elegans

Nature Communications
Animals must sense and acclimatize to environmental temperatures for survival, yet their thermosensing mechanisms other than transient receptor potential (TRP) channels remain poorly understood.
Kohei Ohnishi, Takaaki Sokabe, Toru Miura, Makoto Tominaga, Akane Ohta, Atsushi Kuhara   +5 more
doaj   +1 more source