Results 71 to 80 of about 173,264 (311)

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S., Hamilton, Nicola; id_orcid, Hamilton, N., Butt, Arthur, Hubbard, Paul, Butt, Arthur M., Hamilton, N, Hubbard, P., Butt, AM   +8 more
core   +1 more source

Receptor-interacting protein kinases modulate noise-induced sensory hair cell death [PDF]

Cell Death & Disease, 2014
Receptor-interacting protein (RIP) kinases promote the induction of necrotic cell death pathways. Here we investigated signaling pathways in outer hair cells (OHCs) of adult male CBA/J mice exposed to noise that causes permanent threshold shifts, with a particular focus on RIP kinase-regulated necroptosis.
Zheng, H-W, Chen, J, Sha, S-H
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells

, 2009
Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA, Bennett, DC, Patel, RH, Sviderskaya, EV, Easty, DJ, Sanchez, DP, Lawrence, MA, Anand, P, Korchev, YE   +8 more
core   +1 more source

Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells.

PLoS ONE, 2016
Regulation of gene expression is essential to determining the functional complexity and morphological diversity seen among different cells. Transcriptional regulation is a crucial step in gene expression regulation because the genetic information is ...
Yi Li, Huizhan Liu, Cody L Barta, Paul D Judge, Lidong Zhao, Weiping J Zhang, Shusheng Gong, Kirk W Beisel, David Z Z He   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells [PDF]

, 2012
This article is available open access under a Creative Commons license (http://creativecommons.org/licenses/by-nc-nd/3.0/). Copyright @ 2012 Elsevier Inc.Lymphocytes provide optimal responses against pathogens with minimal inflammatory pathology. However,
Miao, T, Bhullar, P, Ghaffari, Emma, Liu, Mengya, Liu, M, Wang, Ping, Miao, Tizong, Li, Suling, Wang, P, Sebastian, M, Ghaffari, E, Sebastian, Meera, Symonds, Alistair L.J., Li, S, Symonds, ALJ, Bhullar, Punamdip   +15 more
core   +1 more source

Structural Features of an OR37 Glomerulus: A Comparative Study

Frontiers in Neuroanatomy, 2017
In the olfactory bulb (OB) a sophisticated neuronal network mediates the primary processing of sensory information and extensive investigations over the past decades have greatly improved our understanding of the morphology and neuronal organization of ...
Anna-Maria Maier, Heinz Breer, Jörg Strotmann   +2 more
doaj   +1 more source

Morphological evaluation of Merkel cells and small lamellated sensory receptors in the equine foot

American Journal of Veterinary Research, 2017
Abstract OBJECTIVE To examine the equine foot for the presence of sensory receptors including Merkel cells and small lamellated Pacinian-like corpuscles (SLPCs). SAMPLE Forefeet obtained from 7 horses following euthanasia for reasons other than foot disease.
Robert M, Bowker, Lisa S, Lancaster, Diane A, Isbell   +2 more
openaire   +2 more sources

Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear [PDF]

Molecular and Cellular Neuroscience, 2008
Nothing is known about the regulation of nicotinic acetylcholine receptors (nAChRs) in hair cells of the inner ear. MuSK, rapsyn and RIC-3 are accessory molecules associated with muscle and brain nAChR function. We demonstrate that these accessory molecules are expressed in the inner ear raising the possibility of a muscle-like mechanism for clustering
Abdullah A, Osman, Angela D, Schrader, Aubrey J, Hawkes, Omar, Akil, Adam, Bergeron, Lawrence R, Lustig, Dwayne D, Simmons   +6 more
openaire   +2 more sources