Results 101 to 110 of about 1,275,418 (346)

Self-generated neural activity : models and perspective [PDF]

open access: yes, 2009
Poster presentation: The brain is autonomously active and this self-sustained neural activity is in general modulated, but not driven, by the sensory input data stream [1,2].
Gros, Claudius
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Evaluating the impact of denoising diffusion MRI data on tractometry metrics of optic tract abnormalities in glaucoma

open access: yesScientific Reports
Diffusion MRI (dMRI)-based tractometry is a non-invasive neuroimaging method for evaluating white matter tracts in living humans, capable of detecting abnormalities caused by disorders. However, measurement noise in dMRI data often compromises the signal
Daiki Taguma   +2 more
doaj   +1 more source

Simulating development in a real robot: on the concurrent increase of sensory, motor, and neural complexity [PDF]

open access: yes, 2004
We present a quantitative investigation on the effects of a discrete developmental progression on the acquisition of a foveation behavior by a robotic hand-arm-eyes system.
Eggenberger Hotz, Peter   +4 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Correction to: Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human

open access: yesStem Cell Research & Therapy, 2021
Ryota Chijimatsu   +17 more
doaj   +1 more source

Home - About - Disclaimer - Privacy