Results 221 to 230 of about 169,356 (299)

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1543-1550, September 2026.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source

Isolation and partial characterization of OmpF and LsrB as putative Actinobacillus seminis testosterone receptors. [PDF]

World J Microbiol Biotechnol
Ramírez-Paz-Y-Puente GA, Salcedo-Álvarez MO, Avalos-Rangel MA, Vázquez-Cruz C, Cobos-Justos E, Sánchez-Alonso P, Zenteno E, Meneses-Romero EP, Negrete-Abascal E.   +8 more
europepmc   +1 more source

ADSC‐Derived CCL8 Regulates HIF‐1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform

Cancer Science, Volume 117, Issue 9, Page 2480-2495, September 2026.
Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun, Yeseon Son, Jieun Seo, Ki Yong Hong, Junji Fukuda, Do‐Won Jeong, Jong‐Wan Park, Yang‐Sook Chun   +7 more
wiley   +1 more source

Extraction and Purification of Polysaccharides from Thermotolerant <i>Pyropia haitanensis</i> Strain SW-81 and Its Hypolipidemic Effects on Oleic Acid-Induced Lipid Accumulation in HepG2 Cells. [PDF]

Mar Drugs
Zhong J, Ding H, Toppe J, Chen K, Wei M, Chen X, Zhang L, Sun Q, Peng Y, Wu W, Wu W, Wang X.   +11 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, Volume 293, Issue 17, Page 5149-5169, September 2026.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Mass Spectrometric Analysis of <i>N</i>-Glycome of Patatin Proteins from Three Potato Cultivars. [PDF]

Molecules
Li L, Luo S, Wu Y, Zhou Y, Ma Y, Niu J.
europepmc   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, Volume 293, Issue 17, Page 5340-5362, September 2026.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Kinetic and physicochemical modeling of β-galactosidase from Rhynchophorus palmarum larvae. [PDF]

PLoS One
Kambiré SM, Gnanwa MJ, Boa D, Kouadio NEJP, Karamoko BA.   +4 more
europepmc   +1 more source

A Novel Diagnostic Approach for Hepatocellular Carcinoma Using Glycosylated Ferritin

Hepatology Research, Volume 56, Issue 9, Page 1319-1330, September 2026.
The percentage of glycosylated ferritin relative to total ferritin (%GF) is a novel biomarker for hepatocellular carcinoma (HCC), showing diagnostic performance comparable to that of AFP and DCP. We developed the GFAD index by integrating age, sex, %GF, AFP, and DCP, achieving improved diagnostic accuracy with high sensitivity and specificity. ABSTRACT
Akiyo Ishiguro, Yutaka Suehiro, Issei Saeki, Maho Egusa, Norikazu Tanabe, Toshihiko Matsumoto, Tsuyoshi Ishikawa, Yuki Kunimune, Toshihiko Kobayashi, Mitsuaki Nishioka, Taro Takami, Takahiro Yamasaki   +11 more
wiley   +1 more source

Structural insights into cobalamin loading and reactivation of human methionine synthase. [PDF]

Nat Commun
Ferreira DSM, McLennan K, Diamond C, Vollmar M, Kiyani W, Froese DS, Kopec J, Bailey HJ, Chalk R, Baslé A, Elkins JM, Coker JA, Yue WW, McCorvie TJ.   +13 more
europepmc   +1 more source