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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. [PDF]

Intensive Care Medicine, 2017
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened.
Alhazzani, W, Angus, DC, Annane, D, Antonelli, M, Beale, RJ, Bellinghan, GJ, Bernard, GR, Chiche, J-D, Coopersmith, C, De Backer, DP, Dellinger, RP, Evans, LE, Ferrer, R, French, CJ, Fujishima, S, Gerlach, H, Hidalgo, JL, Hollenberg, SM, Jones, AE, Karnad, DR, Kleinpell, RM, Koh, Y, Kumar, A, Levy, MM, Lisboa, TC, Machado, FR, Marini, JJ, Marshall, JC, Mazuski, JE, McIntyre, LA, McLean, AS, Mehta, S, Moreno, RP, Myburgh, J, Navalesi, P, Nishida, O, Nunnally, ME, Osborn, TM, Perner, A, Plunkett, CM, Ranieri, M, Rhodes, A, Rochwerg, B, Rubenfeld, GD, Schorr, CA, Seckel, MA, Sevransky, JE, Seymour, CW, Shieh, L, Shukri, KA, Simpson, SQ, Singer, M, Sprung, CL, Thompson, BT, Townsend, SR, Van der Poll, T, Vincent, J-L, Wiersinga, WJ, Zimmerman, JL   +58 more
core   +5 more sources

Biomarkers in sepsis. [PDF]

Current Opinion in Pulmonary Medicine, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +6 more sources

Augmented renal clearance is not a risk factor for mortality in Enterobacteriaceae bloodstream infections treated with appropriate empiric antimicrobials [PDF]

, 2017
The main objective of the study was to assess whether augmented renal clearance was a risk factor for mortality in a cohort of patients with Enterobacteriaceae sepsis, severe sepsis, or septic shock that all received appropriate antimicrobial therapy ...
Burnham, Jason P, Kollef, Marin H, Micek, Scott T   +2 more
core   +17 more sources

The Role of Connexin Hemichannels in Inflammatory Diseases

Biology, 2022
The connexin protein family consists of approximately 20 members, and is well recognized as the structural unit of the gap junction channels that perforate the plasma membranes of coupled cells and, thereby, mediate intercellular communication.
Bo Peng, Chengping Xu, Shuaiwei Wang, Yijie Zhang, Wei Li   +4 more
doaj   +1 more source

Increase in plasma Niemann–Pick disease type C2 protein is associated with poor prognosis of sepsis

Scientific Reports, 2021
The functional significance of extracellular Niemann–Pick disease type C2 protein (NPC2) is poorly defined. It is not known whether there is an association between plasma NPC2 and sepsis.
Yu Bai, Shuangyi Yin, Vivian Gbordzor, Yu Guo, Qing Bai, Shuaiwei Wang, Xiangyan Wei, Na Chen, Yijie Zhang, Wei Li   +9 more
doaj   +1 more source

National Antimicrobial Stewardship Activities in Primary and Secondary Care in England 2021–22 (ESPAUR Report)

Medical Sciences Forum, 2023
A summary of key national primary and secondary care antimicrobial stewardship interventions led by the UK Health Security Agency (UKHSA) are highlighted.
Ella Casale, Catherine V. Hayes, Donna Lecky, Luke O’Neil, Eirwen Sides, Emily Cooper, Fionna Pursey, Sejal Parekh, Eleanor J. Harvey, Diane Ashiru-Oredope   +9 more
doaj   +1 more source

Introduction to the ESPAUR Webinar and Report 2021–2022: Key Findings and Stakeholder Engagement

Medical Sciences Forum, 2023
During the coronavirus (COVID-19) pandemic, we saw significant decreases in the incidence of bloodstream infections (BSIs), antibiotic-resistant infections, and the burden of resistant infections.
Neil Cunningham, Ella Casale, Carry Triggs-Hodge, Colin S. Brown, Russell Hope, Diane Ashiru-Oredope, Susan Hopkins   +6 more
doaj   +1 more source

Knowledge and Attitudes about Antibiotics and Antibiotic Resistance of 2404 UK Healthcare Workers

Antibiotics, 2022
Background: Using the COM-B model as a framework, an EU-wide survey aimed to ascertain multidisciplinary healthcare workers’ (HCWs’) knowledge, attitudes and behaviours towards antibiotics, antibiotic use and antibiotic resistance.
Diane Ashiru-Oredope, Ella Casale, Eleanor Harvey, Eno Umoh, Sagar Vasandani, Jacqui Reilly, Susan Hopkins   +6 more
doaj   +1 more source

Improving the Quantification of Colorimetric Signals in Paper-Based Immunosensors with an Open-Source Reader

Sensors, 2022
Measuring the colorimetric signals produced by the biospecific accumulation of colorimetric probes and recording the results is a key feature for next-generation paper-based rapid tests.
Steven M. Russell, Alejandra Alba-Patiño, Andreu Vaquer, Antonio Clemente, Roberto de la Rica   +4 more
doaj   +1 more source

Statement of Peer Review

Medical Sciences Forum, 2023
In submitting conference proceedings to Medical Sciences Forum, the volume editors of the proceedings certify to the publisher that all papers published in this volume have been subjected to peer review administered by the volume editors [...]
Diane Ashiru-Oredope, Carry Triggs-Hodge, Jordan Charlesworth   +2 more
doaj   +1 more source