Results 1 to 10 of about 815,905 (331)

The Role of Connexin Hemichannels in Inflammatory Diseases

Biology, 2022
The connexin protein family consists of approximately 20 members, and is well recognized as the structural unit of the gap junction channels that perforate the plasma membranes of coupled cells and, thereby, mediate intercellular communication.
Bo Peng, Chengping Xu, Shuaiwei Wang, Yijie Zhang, Wei Li   +4 more
doaj   +1 more source

Increase in plasma Niemann–Pick disease type C2 protein is associated with poor prognosis of sepsis

Scientific Reports, 2021
The functional significance of extracellular Niemann–Pick disease type C2 protein (NPC2) is poorly defined. It is not known whether there is an association between plasma NPC2 and sepsis.
Yu Bai, Shuangyi Yin, Vivian Gbordzor, Yu Guo, Qing Bai, Shuaiwei Wang, Xiangyan Wei, Na Chen, Yijie Zhang, Wei Li   +9 more
doaj   +1 more source

National Antimicrobial Stewardship Activities in Primary and Secondary Care in England 2021–22 (ESPAUR Report)

Medical Sciences Forum, 2023
A summary of key national primary and secondary care antimicrobial stewardship interventions led by the UK Health Security Agency (UKHSA) are highlighted.
Ella Casale, Catherine V. Hayes, Donna Lecky, Luke O’Neil, Eirwen Sides, Emily Cooper, Fionna Pursey, Sejal Parekh, Eleanor J. Harvey, Diane Ashiru-Oredope   +9 more
doaj   +1 more source

Introduction to the ESPAUR Webinar and Report 2021–2022: Key Findings and Stakeholder Engagement

Medical Sciences Forum, 2023
During the coronavirus (COVID-19) pandemic, we saw significant decreases in the incidence of bloodstream infections (BSIs), antibiotic-resistant infections, and the burden of resistant infections.
Neil Cunningham, Ella Casale, Carry Triggs-Hodge, Colin S. Brown, Russell Hope, Diane Ashiru-Oredope, Susan Hopkins   +6 more
doaj   +1 more source

Knowledge and Attitudes about Antibiotics and Antibiotic Resistance of 2404 UK Healthcare Workers

Antibiotics, 2022
Background: Using the COM-B model as a framework, an EU-wide survey aimed to ascertain multidisciplinary healthcare workers’ (HCWs’) knowledge, attitudes and behaviours towards antibiotics, antibiotic use and antibiotic resistance.
Diane Ashiru-Oredope, Ella Casale, Eleanor Harvey, Eno Umoh, Sagar Vasandani, Jacqui Reilly, Susan Hopkins   +6 more
doaj   +1 more source

Improving the Quantification of Colorimetric Signals in Paper-Based Immunosensors with an Open-Source Reader

Sensors, 2022
Measuring the colorimetric signals produced by the biospecific accumulation of colorimetric probes and recording the results is a key feature for next-generation paper-based rapid tests.
Steven M. Russell, Alejandra Alba-Patiño, Andreu Vaquer, Antonio Clemente, Roberto de la Rica   +4 more
doaj   +1 more source

Antimicrobial Resistance: Professional and Public Education, Engagement, and Training Activities 2021–2022 (ESPAUR Report)

Medical Sciences Forum, 2023
This is a summary of initiatives to engage and educate the general public and healthcare professionals about antimicrobial use, stewardship and resistance, as covered in the 2021–2022 English Surveillance Programme for Antimicrobial Utilisation and ...
Catherine V. Hayes, Jordan Charlesworth, Diane Ashiru-Oredope, Eirwen Sides, Amy Jackson, Emily Cooper, Brieze Read, Donna Seaton, Lorna Flintham, Harpreet Sidhu, Donna M. Lecky   +10 more
doaj   +1 more source

Female-Specific Association of Plasma N-Terminal Pro-Brain Natriuretic Peptide With Organ Dysfunction and Prognosis in Sepsis: A Retrospective Study

Critical Care Explorations, 2021
Objectives:. The plasma level of N-terminal pro-brain natriuretic peptide is regulated by sex hormones. It has been controversial whether N-terminal pro-brain natriuretic peptide is a prognosis marker for sepsis.
Shuangyi Yin, PhD, Yijie Zhang, MD, Yu Guo, MD, Qing Bai, MD, Zhibo Lu, MD, Na Chen, MD, Edmund J. Miller, PhD, Wei Li, MD, PhD   +7 more
doaj   +1 more source

Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury

Mediators of Inflammation, 2020
Connexin (Cx) family members form hemichannels (HCs) and gap junctions (GJs). Biological functions of Cx HCs have not been adequately characterized due to the inability to selectively target HCs or GJs. Recently, we developed a 6-mer peptide mimetic (P5)
Shuaiwei Wang, Yafang Sun, Yu Bai, Nannan Zhou, Na Chen, Edmund J. Miller, Yijie Zhang, Wei Li   +7 more
doaj   +1 more source

Statement of Peer Review

Medical Sciences Forum, 2023
In submitting conference proceedings to Medical Sciences Forum, the volume editors of the proceedings certify to the publisher that all papers published in this volume have been subjected to peer review administered by the volume editors [...]
Diane Ashiru-Oredope, Carry Triggs-Hodge, Jordan Charlesworth   +2 more
doaj   +1 more source