Results 41 to 50 of about 583,528 (304)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

BMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta   +27 more
doaj   +1 more source

Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club [PDF]

, 2005
Sepsis is a systemic inflammatory response to the presence of infection, mediated via the production of many cytokines, including tumour necrosis factor alpha (TNF-alpha), interleukin (IL)-6, and IL-1, which cause changes in the circulation ...
Wong, F., Balk, R., Patch, D., Garcia-Tsao, G., Navasa, Miquel, Hoefs, J., Soriano Pastor, Germán, Moreau, R., Wong, Florence, Moreau, Richard, Bernardi, M., Christman, B., Soriano, G., Navasa, M., Bernardi, Mauro, HOEFS J., BALK R., CHRISTMAN B., NAVASA M., WONG F., SORIANO G., MOREAU R., PATCH D., GARCIA TSAO G.   +23 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Long-term trends in incidence and mortality in Staphylococcus aureus bacteraemia; a retrospective population-based study from Central Norway 1996–2022

BMC Infectious Diseases
Objectives This study aims to examine changes in incidence and mortality in Staphylococcus aureus bacteraemia (SAB) over time and between sexes, describe clinical characteristics and asses their associations with 30-day mortality. Methods We included 837
Ingvild Haugan, Helene Marie Flatby, Birgitta Ehrnström, Nina Vibeche Skei, Randi Marie Mohus, Erik Solligård, Frode Width Gran, Lise Tuset Gustad, Stian Lydersen, Christina Gabrielsen Ås, Jan Kristian Damås, Jan Egil Afset   +11 more
doaj   +1 more source

Association between sepsis incidence and regional socioeconomic deprivation and health care capacity in Germany – an ecological study

BMC Public Health, 2021
Background Sepsis is a substantial health care burden. Data on regional variation in sepsis incidence in Germany and any possible associations with regional socioeconomic deprivation and health care capacity is lacking.
Norman Rose, Claudia Matthäus-Krämer, Daniel Schwarzkopf, André Scherag, Sebastian Born, Konrad Reinhart, Carolin Fleischmann-Struzek   +6 more
doaj   +1 more source

Time-to-positivity of blood cultures in children with sepsis [PDF]

, 2018
Background: Blood cultures are essential for the diagnosis and further appropriate treatment in children with suspected sepsis. In most hospitals, children will be empirically treated or closely monitored for at least 48 h awaiting results of blood ...
Thomas Riedel, Heininger, Ulrich, Kahlert, Christian R., Stocker, M., Dierig, Alexa, Posfay Barbe, Klara, Hasters, P., Aebi, Christoph, Eric Giannoni, Hasters, Paul, Christoph Berger, Schlapbach, Luregn J, Riedel, T., Posfay-Barbe, Klara M, Philipp K. A. Agyeman, Giannoni, E., Niederer-Loher, A., Luregn J. Schlapbach, Posfay-Barbe, K.M., Christoph Aebi, Berger, Christoph, Paul Hasters, Agyeman, Philipp, Bernhard-Stirnemann, Sara, Stocker, Martin, Kahlert, C.R., Donas, Alex, Alexa Dierig, null null, Schlapbach, Luregn Jan, Martin Stocker, Anita Niederer-Loher, Riedel, Thomas, Donas, A., Klara M. Posfay-Barbe, Niederer-Loher, Anita, Schlapbach, L.J., Agyeman, PKA, Sara Bernhard-Stirnemann, Posfay-Barbe, Klara M., Berger, C., Heininger, U., Aebi, C., Relly, Christa, Agyeman, Philipp K A, Berger, Christoph; https://orcid.org/, Christian R. Kahlert, Bernhard-Stirnemann, S., Alex Donas, Swiss Pediatric Sepsis Study, Relly, C., Dierig, A., Agyeman, Philipp K. A., Kahlert, Christian R, Schlapbach, Luregn J., Christa Relly, Giannoni, Eric, Ulrich Heininger   +57 more
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Primer Consenso Colombiano en Sepsis

Revista Colombiana de Cirugía, 2006
La sepsis, sepsis severa y el choque séptico tienen una incidencia alta y conllevan a una alta mortalidad, morbilidad y costos. Es por esto que la AMCI y la ACIN decidieron realizar un consenso de diagnóstico y tratamiento de sepsis con los siguientes ...
Marcos I. Restrepo, Carmelo Dueñas, Marco González, Guillermo Ortiz, Carlos Álvarez, Marcela Granados, Carlos Acosta, Arturo Arias, Luis H. Atehortúa, Rubén Camargo, Martín Carvajal, Gisela de la Rosa, Julio Durán, Juan L. Echeverri, Bladimir Gil, Carlos Hurtado, Ernesto Martínez, Carlos Rebolledo, Carlos Saavedra, Julio Sandoval, Julio Velandia, José A. Vélez, Juan D. Vélez, Representantes de los comités de la Asociación Colombiana de Medicina Intensiva y Cuidado Intensivo (AMCI) y la Asociación Colombiana de Infectología (ACIN)   +23 more
doaj  

IL17F+ naïve and IFNγ+ memory CD8 T cells drive hepatic dysfunction in the cecal ligation and puncture model of sepsis

Molecular Medicine
T cell memory significantly alters the immune response and organ dysfunction induced by the murine cecal ligation and puncture (CLP) model of sepsis.
Matthew D. Taylor, Omar Geier, Alexandria Z. Byskosh, Ekaterina Murzin, Ana Nedeljkovic-Kurepa, Grace M. Fisler, Mabel N. Abraham, Mariana R. Brewer, James A. Lederer, Clifford S. Deutschman   +9 more
doaj   +1 more source