Results 41 to 50 of about 536,044 (309)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Long-term trends in incidence and mortality in Staphylococcus aureus bacteraemia; a retrospective population-based study from Central Norway 1996–2022

BMC Infectious Diseases
Objectives This study aims to examine changes in incidence and mortality in Staphylococcus aureus bacteraemia (SAB) over time and between sexes, describe clinical characteristics and asses their associations with 30-day mortality. Methods We included 837
Ingvild Haugan, Helene Marie Flatby, Birgitta Ehrnström, Nina Vibeche Skei, Randi Marie Mohus, Erik Solligård, Frode Width Gran, Lise Tuset Gustad, Stian Lydersen, Christina Gabrielsen Ås, Jan Kristian Damås, Jan Egil Afset   +11 more
doaj   +1 more source

DENTAL SEPSIS [PDF]

BMJ, 1914
n ...
openaire   +4 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Towards a novel carbon device for the treatment of sepsis [PDF]

, 2004
Sepsis is a systemic inflammatory response to infection in which the balance of pro- andanti-inflammatory mediators, which normally isolate and eliminate infection, is disrupted.
Phillips, G.J., Courtney, J.M., Kozynchenko, O.P., Barnes, L.M., Lloyd, A.W., Melillo, M., Murphy, M.C., Sandeman, S.R., Tennison, S.R., Howell, C.A., Gaylor, J.D.S., Davies, J.G., Mikhalovsky, S.V.   +12 more
core  

IL17F+ naïve and IFNγ+ memory CD8 T cells drive hepatic dysfunction in the cecal ligation and puncture model of sepsis

Molecular Medicine
T cell memory significantly alters the immune response and organ dysfunction induced by the murine cecal ligation and puncture (CLP) model of sepsis.
Matthew D. Taylor, Omar Geier, Alexandria Z. Byskosh, Ekaterina Murzin, Ana Nedeljkovic-Kurepa, Grace M. Fisler, Mabel N. Abraham, Mariana R. Brewer, James A. Lederer, Clifford S. Deutschman   +9 more
doaj   +1 more source

Decoding lung-kidney interactions in sepsis: an integrated view of molecular mechanisms, pathophysiology, and therapeutic interventions

Frontiers in Immunology
Sepsis, a great health concern globally, is characterized by multi-organ dysfunction and high mortality rate. As highly vascularized organs, the kidney and lung are the most susceptible in sepsis.
Chenye Ma, Hongyi Li, Zirong Chen, Heng Song, Yuze Wang, Zhihui Liu, Xuefan Bu, Xianfei Ding, Hanfang Si, Jinghua Yang, Tongwen Sun   +10 more
doaj   +1 more source

Gasdermins in sepsis

Frontiers in Immunology, 2023
Sepsis is a hyper-heterogeneous syndrome in which the systemic inflammatory response persists throughout the course of the disease and the inflammatory and immune responses are dynamically altered at different pathogenic stages. Gasdermins (GSDMs) proteins are pore-forming executors in the membrane, subsequently mediating the release of pro ...
Wenhua Wang, Zhihui He, Zhihui He
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sepsis beim Hund: Interleukin-6 als prognostischer Parameter [PDF]

, 2007
Wie auch in der Humanmedizin stellen Sepsis und SIRS den behandelnden Arzt in der Veterinärmedizin vor eine große Herausforderung. Eine optimale therapeutische Intervention setzt besonders die Früherkennung dieser Erkrankungen und damit auch die ...
Rau, Stefanie Maria
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