Circulating levels of micronutrients and risk of infections: a Mendelian randomization study
BMC Medicine, 2023 Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections.
Helene M. Flatby +4 more
doaj +1 more source
Antimicrobial Resistance in England 2017 to 2021 (ESPAUR Report 2021–22)
Medical Sciences Forum, 2023 The English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) antimicrobial resistance (AMR) chapter reports on bacterial, viral, and fungal AMR trends between 2017 and 2021 in England.
Rebecca Guy +9 more
doaj +1 more source
Pathological Signal-Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation. [PDF]
Adv Sci (Weinh)Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Liu Y +7 more
europepmc +2 more sources
New approaches to preventing, diagnosing, and treating neonatal sepsis. [PDF]
, 2010 Karen Edmond and Anita Zaidi highlight new approaches that could reduce the burden of neonatal sepsis ...
Karen Edmond +6 more
core +2 more sources
Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
wiley +1 more source
Digital PCR applications for the diagnosis and management of infection in critical care medicine
Critical Care, 2022 Infection (either community acquired or nosocomial) is a major cause of morbidity and mortality in critical care medicine. Sepsis is present in up to 30% of all ICU patients.
Irene Merino +5 more
doaj +1 more source
Sphingolipidomics in Translational Sepsis Research–Biomedical Considerations and Perspectives
Frontiers in Medicine, 2021 Scientific Background: Sphingolipids are a highly diverse group of lipids with respect to physicochemical properties controlling either structure, distribution, or function, all of them regulating cellular response in health and disease.
Ralf A. Claus +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
National Sepsis Report 2016 [PDF]
, 2017 In 2016, the definition of sepsis was changed from a clinical syndrome defined by a systemic inflammatory response (SIRS) due to infection to a life-threatening organ dysfunction caused by a dysregulated immune response to infection (formerly severe ...
National Sepsis Programme.
core +1 more source
Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis [PDF]
, 1994 Die Diskussion am Ende des Artikels wurde gelöscht (§137l UrhG).Background The proteolytic enzyme elastase released by granulocytes (polymorphonuclear leukocytes [PMN]) in high concentrations during sepsis causes degradation of essential plasma proteins,
Schildberg, Friedrich-Wilhelm +7 more
core +1 more source