Results 21 to 30 of about 895,147 (354)

Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis [PDF]

open access: yes, 2019
BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis.
Bergmann, A.   +4 more
core   +1 more source

Epigenetics of Sepsis

open access: yesCritical Care Medicine, 2020
Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Binnie, Alexandra   +5 more
openaire   +3 more sources

Proteomic and epigenomic markers of sepsis-induced delirium (SID) [PDF]

open access: yes, 2015
In elderly population sepsis is one of the leading causes of intensive care unit (ICU) admissions in the United States. Sepsis-induced delirium (SID) is the most frequent cause of delirium in ICU (Martin et al., 2010). Together delirium and SID represent
Adonis eSfera   +5 more
core   +2 more sources

Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

open access: yesCritical Care, 2018
Background This study aimed to evaluate the accuracy of procalcitonin (PCT) serum concentrations to diagnose Gram-negative bacteremia and the association of PCT serum concentrations with more specific pathogens and the focus of infection.
Daniel O. Thomas-Rüddel   +6 more
doaj   +1 more source

Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]

open access: yes, 2013
Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario   +10 more
core   +2 more sources

Takotsubo cardiomyopathy and sepsis: a systematic review [PDF]

open access: yes, 2017
Takotsubo cardiomyopathy (TTC) is characterized by a systolic dysfunction localized in the apical and medial aspect of the left ventricle. It is usually related to physical or emotional stress.
Agarwal V   +15 more
core   +1 more source

Biomarkers in sepsis. [PDF]

open access: yes, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +1 more source

Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study

open access: yesScientific Reports, 2022
Observational studies have indicated an association between iron status and risk of sepsis and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of sepsis and risk of being hospitalized with COVID-19, performing a two ...
Randi Marie Mohus   +8 more
doaj   +1 more source

Sepsis Education and Training in Medical School [PDF]

open access: yes, 2020
Purpose: According to the National Institutes of Health, severe sepsis strikes more than one million Americans every year. Despite the extensive research that has gone into creating the different risk stratification tools for sepsis, there is still a ...
Gaieski, MD, David F.   +2 more
core   +1 more source

Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis [PDF]

open access: yes, 1994
Die Diskussion am Ende des Artikels wurde gelöscht (§137l UrhG).Background The proteolytic enzyme elastase released by granulocytes (polymorphonuclear leukocytes [PMN]) in high concentrations during sepsis causes degradation of essential plasma proteins,
Ertel, Wolfgang   +6 more
core   +1 more source

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