Results 61 to 70 of about 583,528 (304)

Tumor Necrosis Factor-α as a Diagnostic Marker for Neonatal Sepsis: A Meta-Analysis

The Scientific World Journal, 2014
Neonatal sepsis (NS) is an important cause of mortality in newborns and life-threatening disorder in infants. The meta-analysis was performed to investigate the diagnosis value of tumor necrosis factor-α (TNF-α) test in NS.
Bokun Lv, Jie Huang, Haining Yuan, Wenying Yan, Guang Hu, Jian Wang   +5 more
doaj   +1 more source

The role of peroxisome proliferator-activated receptor gamma during sepsis-induced lymphopenia [PDF]

, 2011
Sepsis is one of the most common diseases on intensive care units all over the world and accounts there for the highest mortality rate. One of the hallmarks of sepsis is an accelerated T-cell apoptosis, resulting in a compromised immune state with the ...
Schmidt, Martina
core  

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Prognostic Value of International Normalized Ratio and Thrombocytopenia in Early Risk Stratification of Septic Patients

Biomedicines
Background/Objective: Coagulopathy is a hallmark of sepsis, associated with poor outcomes. Although platelet count has commonly been used for risk stratification, its prognostic value has remained limited.
Sofía Tejada, Andrés Giglio, Maria Aranda, Antonia Socias, Alberto del Castillo, Joana Mena, Sara Franco, Maria Ortega, Yasmina Nieto, Marcio Borges-Sa   +9 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Incidence of and mortality due to sepsis, severe sepsis and septic shock in Italian Pediatric Intensive Care Units: a prospective national survey. Intensive Care Medicine

, 2008
Objectives: The objective was to assess the incidence of sepsis, severe sepsis and septic shock and their mortality in Italian Pediatric Intensive Care Units (PICUs). Design: This is a prospective, observational, multi-center, 1-year study.
Musicco M, Salvo I, Antonelli M, Wolfler A, Italian Pediat Sepsis Study Grp, Silvani P   +5 more
core   +1 more source

Dynamically Actuated Reconfigurable Topographical Surface Enables Active Control of Implant‐Associated Infections

Advanced Functional Materials, EarlyView.
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash, Jihun Lee, J. Scott VanEpps, Sungmin Nam, Jouha Min   +4 more
wiley   +1 more source

Inflammatory mediators, infection, sepsis, and multiorgan failure after severe trauma [PDF]

, 1992
The relation of (multiple) organ failure (OF) to the release of inflammatory mediators and the incidence of infection and sepsis was studied prospectively in 100 patients with multiple trauma (injury severity score=37).
Waydhas, Christian, Trupka, Arnold, Nast-Kolb, Dieter, Schweiberer, Leonhard, Jochum, Marianne, Fritz, Hans, Lenk, Susann, Duswald, Karl-Heimo   +7 more
core   +1 more source

Circulating NETs enable early identification of thrombotic risk in sepsis at emergency care onset

Frontiers in Immunology
IntroductionSepsis involves a dysregulated host response to infection and is frequently complicated by coagulopathy, contributing to organ dysfunction and mortality.
Sofia Tejada, Antonio Clemente, Antonio Clemente, Antonia Socias, Antonia Socias, Maria Aranda, Maria Aranda, Alberto del Castillo, Alberto del Castillo, Joana Mena, Joana Mena, Joana Mª Ribas, Joana Mª Ribas, Luisa Martín, Luisa Martín, Karla Milagritos Llerena, Karla Milagritos Llerena, María Magdalena Arellano, María Magdalena Arellano, Miguel Agudo, Roberto de la Rica, Roberto de la Rica, Marcio Borges, Marcio Borges   +23 more
doaj   +1 more source

Enhancing sepsis biomarker development: key considerations from public and private perspectives [PDF]

Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to facilitate the transition of sepsis biomarkers into clinical practice.
Rodriguez-Manzano, J, Rodriguez-Manzano, Jesus, Payen, D, Payen, Didier, on behalf of the Sepsis biomarker workshop group, Scicluna, Brendon P., Carrol, ED, Scicluna, BP, Llitjos, JF, François, B, Osuchowski, Marcin F., Carrol, Enitan D., Bonneville, Marc, François, Bruno, Witte, Stephan, Bonneville, M, Llitjos, Jean-Francois, Witte, S, Osuchowski, MF, Randolph, AG, Randolph, Adrienne G., Sepsis biomarker workshop group   +21 more
core   +1 more source