Results 71 to 80 of about 583,528 (304)

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study [PDF]

, 2018
To assess the epidemiology of blood culture-proven early- (EOS) and late-onset neonatal sepsis (LOS).All newborn infants admitted to tertiary care neonatal intensive care units in Switzerland and presenting with blood culture-proven sepsis between ...
Heininger, Ulrich, Niederer-Loher, Anita, Kahlert, Christian R., Stocker, M., Schlapbach, L.J., Agyeman, PKA, Posfay Barbe, Klara, Hasters, P., Posfay-Barbe, Klara M., Heininger, U., Berger, C., Aebi, Christoph, Aebi, C., Relly, Christa, Spycher, Ben D, Hasters, Paul, Schlapbach, Luregn J, Riedel, T., Agyeman, Philipp K A, Posfay-Barbe, Klara M, Giannoni, E., Niederer-Loher, A., Berger, Christoph; https://orcid.org/, Kuehni, C., Posfay-Barbe, K.M., Spycher, Ben D., Berger, Christoph, Bernhard-Stirnemann, S., Swiss Pediatric Sepsis Study, Relly, C., Kuehni, Claudia, Spycher, B.D., Bernhard-Stirnemann, Sara, Stocker, Martin, Kahlert, C.R., Agyeman, Philipp K. A., Kahlert, Christian R, Donas, Alex, Leone, Antonio, Schlapbach, Luregn J., Riedel, Thomas, Sepsis Study, Swiss Pediatric, Donas, A., Leone, A., Giannoni, Eric   +44 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Clinical validation of continuous glucose monitoring in glycemic management of critically ill sepsis patients: A prospective randomized clinical study

Journal of International Medical Research
Objective This study assessed the accuracy, clinical effectiveness, and utility of continuous glucose monitoring compared with conventional methods in critically ill patients with sepsis. Methods From July 2023 to July 2025, 60 patients with sepsis (mean
Qin Si, Yifeng Mao, Jian Lan, Wei Lu, Cheng Zheng, Qian Zhu, Xijiang Zhang   +6 more
doaj   +1 more source

Incidence and outcome of group B streptococcal sepsis in infants in Switzerland [PDF]

, 2016
The incidence and outcome of group B streptococcal (GBS) sepsis were assessed prospectively between September 2011 and February 2015 in all tertiary care pediatric hospitals of Switzerland. We describe a low incidence of GBS early-onset sepsis (0.12/1000
Heininger, Ulrich, Niederer-Loher, Anita, Stocker, M., for the Swiss Pediatric Sepsis Study Group, Schlapbach, L.J., Baer, W., Posfay Barbe, Klara, Hasters, P., Posfay-Barbe, Klara M., Berger, C., Heininger, U., Aebi, Christoph, Aebi, C., Relly, Christa, Hasters, Paul, Schlapbach, Luregn J, Posfay-Barbe, Klara M, Kahlert, C., Giannoni, E., Niederer-Loher, A., Berger, Christoph; https://orcid.org/, Posfay-Barbe, K.M., Schlapbach, Luregn, Berger, Christoph, Agyeman, P., Relly, C., Agyeman, Philipp, Stocker, Martin, Konetzny, G., Donas, Alex, Leone, Antonio, Konetzny, Gabriel, Schlapbach, Luregn J., Schlapbach, Luregn Jan, Donas, A., Leone, A., Kahlert, Christian, Giannoni, Eric, Baer, Walter   +38 more
core   +2 more sources

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Biomarkers to guide sepsis management

Annals of Intensive Care
Background: Sepsis remains a major cause of morbidity and mortality. Precision therapeutics are now regarded as a novel prospective to improve outcome.
Vasiliki Bourika, Evangelia-Areti Rekoumi, Evangelos J. Giamarellos-Bourboulis   +2 more
doaj   +1 more source

Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response

Journal of Lipid Research, 2013
Plasma secretion of acid sphingomyelinase is a hallmark of cellular stress response resulting in the formation of membrane embedded ceramide-enriched lipid rafts and the reorganization of receptor complexes.
Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus F. Blaess, Anja Lueth, Hans-Peter Deigner, Michael Bauer, Ralf A. Claus   +10 more
doaj   +1 more source

Neonatal Sepsis-Culture Positive Sepsis vs Clinical Sepsis

International Journal of Medical and Dental Sciences, 2017
<p><strong>Background</strong>: The incidence of sepsis is increasing globally, with high morbidity and mortality. Diagnosis of neonatal sepsis is still a clinical and laboratory challenge. Though blood culture is gold standard, it sometimes gives false negative result.
Purbasha Ghosh, Rabindra Nath Misra, Retina Paul   +2 more
openaire   +2 more sources

Predictors of Positive Blood Culture and Deaths Among Neonates with Suspected Neonatal Sepsis in a Tertiary Hospital, Mwanza-Tanzania. [PDF]

, 2010
Neonatal sepsis is a significant cause of morbidity and mortality in neonates. Appropriate clinical diagnosis and empirical treatment in a given setting is crucial as pathogens of bacterial sepsis and antibiotic sensitivity pattern can considerably vary ...
Kamugisha, Erasmus, Jeremiah, Seni, Mwizamholya Damas L, Stephen E Mshana, Kamugisha Erasmus, Erasmus Kamugisha, Damas L Mwizamholya, Mshana Stephen E, Mwizamholya, Damas L, Kayange, Neema, Neema Kayange, Jeremiah Seni, Kayange Neema, Mshana, Stephen E, Seni Jeremiah   +14 more
core   +2 more sources