Results 11 to 20 of about 875,517 (356)

Female-Specific Association of Plasma N-Terminal Pro-Brain Natriuretic Peptide With Organ Dysfunction and Prognosis in Sepsis: A Retrospective Study

open access: yesCritical Care Explorations, 2021
Objectives:. The plasma level of N-terminal pro-brain natriuretic peptide is regulated by sex hormones. It has been controversial whether N-terminal pro-brain natriuretic peptide is a prognosis marker for sepsis.
Shuangyi Yin, PhD   +7 more
doaj   +1 more source

Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network [PDF]

open access: yes, 2018
BACKGROUND: Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units ...
Agodi A   +15 more
core   +1 more source

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]

open access: yes, 2012
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H.   +11 more
core   +3 more sources

Lactate concentration gradient from right atrium to pulmonary artery: a commentary [PDF]

open access: yes, 2005
Inadequate myocardial performance is a common complication of severe sepsis. Studies in humans strongly argue against a decrease in coronary blood flow in the pathogenesis of this sepsis-induced cardiac injury.
Creteur, Jacques
core   +2 more sources

PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis [PDF]

open access: yes, 2019
Sepsis‐associated acute kidney injury (AKI) is a significant problem in critically ill children and adults resulting in increased morbidity and mortality. Fundamental mechanisms contributing to sepsis‐associated AKI are poorly understood.
Bennion, Brock G   +10 more
core   +2 more sources

Composed endotypes to guide antibiotic discontinuation in sepsis

open access: yesCritical Care, 2019
Overuse of empiric antibiotic therapy in the ICU is responsible for promoting the dissemination of multidrug-resistant (MDR) bacteria. Shortened antibiotic treatment duration could contribute to palliating the emergence of MDR.
Jesus F. Bermejo-Martin   +4 more
doaj   +1 more source

A snapshot of compliance with the sepsis six care bundle in two acute hospitals in the West Midlands, UK [PDF]

open access: yes, 2019
The sepsis six care bundle has been adopted by hospitals in England and Wales for the management of patients with sepsis, with the aim of increasing survival when all elements of the bundle are achieved.
Frankling, Catriona   +6 more
core   +1 more source

Biomarkers in sepsis. [PDF]

open access: yes, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +1 more source

Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

open access: yesCritical Care, 2018
Background This study aimed to evaluate the accuracy of procalcitonin (PCT) serum concentrations to diagnose Gram-negative bacteremia and the association of PCT serum concentrations with more specific pathogens and the focus of infection.
Daniel O. Thomas-Rüddel   +6 more
doaj   +1 more source

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