Results 11 to 20 of about 815,905 (331)

Biomarkers in sepsis. [PDF]

open access: yesCurrent Opinion in Pulmonary Medicine, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +6 more sources

The Endothelium in Sepsis [PDF]

open access: yesShock, 2016
Sepsis affects practically all aspects of endothelial cell (EC) function and is thought to be the key factor in the progression from sepsis to organ failure. Endothelial functions affected by sepsis include vasoregulation, barrier function, inflammation, and hemostasis.
Ince, Can   +8 more
openaire   +7 more sources

Sesamin attenuates intestinal injury in sepsis via the HMGB1/TLR4/IL-33 signalling pathway

open access: yesPharmaceutical Biology, 2020
Context Sepsis is currently one of the leading causes of death in intensive care units (ICUs). Sesamin was previously reported to inhibit inflammation. However, no studies have revealed the impact of sesamin on sepsis.
Zhi-Ling Li   +5 more
doaj   +1 more source

Evaluation of updated sepsis scoring systems and systemic inflammatory response syndrome criteria and their association with sepsis in equine neonates [PDF]

open access: yes, 2018
BackgroundThe original equine sepsis score provided a method of identifying foals with sepsis. New variables associated with sepsis have been evaluated, but the sepsis score has not been updated.ObjectivesTo evaluate the sensitivity and specificity of 2 ...
Bates   +36 more
core   +1 more source

Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. [PDF]

open access: yes, 2016
ObjectivesThiamin deficiency is highly prevalent in patients with sepsis, but the mechanism by which sepsis induces thiamin deficiency is unknown. This study aimed to determine the influence of various severity of sepsis on carrier-mediated intestinal ...
Fang, Liwei   +4 more
core   +2 more sources

Composed endotypes to guide antibiotic discontinuation in sepsis

open access: yesCritical Care, 2019
Overuse of empiric antibiotic therapy in the ICU is responsible for promoting the dissemination of multidrug-resistant (MDR) bacteria. Shortened antibiotic treatment duration could contribute to palliating the emergence of MDR.
Jesus F. Bermejo-Martin   +4 more
doaj   +1 more source

Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network [PDF]

open access: yes, 2018
BACKGROUND: Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units ...
Agodi A   +15 more
core   +1 more source

Bacterial Sepsis in Brazilian Children: A Trend Analysis from 1992 to 2006 [PDF]

open access: yes, 2011
BACKGROUND: The objective of this study was to determine the epidemiology of hospitalized pediatric sepsis in Brazil (1992–2006) and to compare mortality caused by sepsis to that caused by other major childhood diseases.
Andrade, Maria Cristina   +5 more
core   +8 more sources

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