Results 11 to 20 of about 1,046,938 (380)
New England Journal of Medicine, 2017 Commentum to "Levosimendan for the Prevention of Acute Organ Dysfunction in ...
Morelli, Andrea, Tritapepe, Luigi
core +14 more sources
Current Opinion in Pulmonary Medicine, 2013 Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core +6 more sources
How to use biomarkers of infection or sepsis at the bedside: guide to clinicians
Intensive Care Medicine, 2023 Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or
P. Póvoa +14 more
semanticscholar +1 more source
The Endothelium in Sepsis [PDF]
Shock, 2016 Sepsis affects practically all aspects of endothelial cell (EC) function and is thought to be the key factor in the progression from sepsis to organ failure. Endothelial functions affected by sepsis include vasoregulation, barrier function, inflammation, and hemostasis.
Ince, Can +8 more
openaire +7 more sources
Sesamin attenuates intestinal injury in sepsis via the HMGB1/TLR4/IL-33 signalling pathway
Pharmaceutical Biology, 2020 Context Sepsis is currently one of the leading causes of death in intensive care units (ICUs). Sesamin was previously reported to inhibit inflammation. However, no studies have revealed the impact of sesamin on sepsis.
Zhi-Ling Li +5 more
doaj +1 more source
Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network [PDF]
, 2018 BACKGROUND: Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units ...
Agodi A +15 more
core +1 more source
Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]
, 2012 Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H. +11 more
core +3 more sources
A snapshot of compliance with the sepsis six care bundle in two acute hospitals in the West Midlands, UK [PDF]
, 2019 The sepsis six care bundle has been adopted by hospitals in England and Wales for the management of patients with sepsis, with the aim of increasing survival when all elements of the bundle are achieved.
Frankling, Catriona +6 more
core +1 more source
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
Military Medical Research, 2022 Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection.
Di Liu +15 more
semanticscholar +1 more source
Lactate concentration gradient from right atrium to pulmonary artery: a commentary [PDF]
, 2005 Inadequate myocardial performance is a common complication of severe sepsis. Studies in humans strongly argue against a decrease in coronary blood flow in the pathogenesis of this sepsis-induced cardiac injury.
Creteur, Jacques
core +2 more sources