Results 21 to 30 of about 1,046,938 (380)
Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review
Critical Care, 2022 A biomarker describes a measurable indicator of a patient's clinical condition that can be measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis, early disease recognition, risk stratification, appropriate treatment ...
T. Barichello +3 more
semanticscholar +1 more source
Wiener klinische Wochenschrift Education, 2006 Sepsis is a complex syndrome difficult to define, to diagnose and to treat. The term defines a group of clinical conditions caused by the systemic answer of the organism to an infection that can cause the dysfunction of one or more organs (severe sepsis) and death.
Viktor Lenhart +3 more
openaire +6 more sources
Composed endotypes to guide antibiotic discontinuation in sepsis
Critical Care, 2019 Overuse of empiric antibiotic therapy in the ICU is responsible for promoting the dissemination of multidrug-resistant (MDR) bacteria. Shortened antibiotic treatment duration could contribute to palliating the emergence of MDR.
Jesus F. Bermejo-Martin +4 more
doaj +1 more source
PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis [PDF]
, 2019 Sepsis‐associated acute kidney injury (AKI) is a significant problem in critically ill children and adults resulting in increased morbidity and mortality. Fundamental mechanisms contributing to sepsis‐associated AKI are poorly understood.
Bennion, Brock G +10 more
core +2 more sources
Critical Care, 2018 Background This study aimed to evaluate the accuracy of procalcitonin (PCT) serum concentrations to diagnose Gram-negative bacteremia and the association of PCT serum concentrations with more specific pathogens and the focus of infection.
Daniel O. Thomas-Rüddel +6 more
doaj +1 more source
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
Scientific Reports, 2022 Observational studies have indicated an association between iron status and risk of sepsis and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of sepsis and risk of being hospitalized with COVID-19, performing a two ...
Randi Marie Mohus +8 more
doaj +1 more source
Antimicrobial Resistance in England 2017 to 2021 (ESPAUR Report 2021–22)
Medical Sciences Forum, 2023 The English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) antimicrobial resistance (AMR) chapter reports on bacterial, viral, and fungal AMR trends between 2017 and 2021 in England.
Rebecca Guy +9 more
doaj +1 more source
Circulating levels of micronutrients and risk of infections: a Mendelian randomization study
BMC Medicine, 2023 Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections.
Helene M. Flatby +4 more
doaj +1 more source
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]
, 2013 Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario +10 more
core +2 more sources