Results 21 to 30 of about 858,256 (354)

Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study

Scientific Reports, 2022
Observational studies have indicated an association between iron status and risk of sepsis and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of sepsis and risk of being hospitalized with COVID-19, performing a two ...
Randi Marie Mohus, Helene Flatby, Kristin V. Liyanarachi, Andrew T. DeWan, Erik Solligård, Jan Kristian Damås, Bjørn Olav Åsvold, Lise T. Gustad, Tormod Rogne   +8 more
doaj   +1 more source

Biomarkers in sepsis. [PDF]

, 2013
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core   +1 more source

Circulating levels of micronutrients and risk of infections: a Mendelian randomization study

BMC Medicine, 2023
Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections.
Helene M. Flatby, Anuradha Ravi, Jan K. Damås, Erik Solligård, Tormod Rogne   +4 more
doaj   +1 more source

Antimicrobial Resistance in England 2017 to 2021 (ESPAUR Report 2021–22)

Medical Sciences Forum, 2023
The English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) antimicrobial resistance (AMR) chapter reports on bacterial, viral, and fungal AMR trends between 2017 and 2021 in England.
Rebecca Guy, Hannah Higgins, Jamie Rudman, Holly Fountain, Kirsty F. Bennet, Katie L. Hopkins, Alicia Demirjian, Sarah M. Gerver, Mariyam Mirfenderesky, Katherine L. Henderson   +9 more
doaj   +1 more source

Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]

, 2013
Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario, Blincko, Stuart J, Cohen, Jonathan, Curdt, Ingo, Drage, Stephen, Graf, Rolf, Gregory, Mark, Lajaunias, Frédéric, Llewelyn, Martin, Ramaiah, Ravi, Taylor, Amanda L   +10 more
core   +2 more sources

Epigenetics of Sepsis

Critical Care Medicine, 2020
Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Binnie, Alexandra, Tsang, Jennifer L. Y., Hu, Pingzhao, Carrasqueiro, Gabriela, Castelo-Branco, Pedro, dos Santos, Claudia C.   +5 more
openaire   +3 more sources

Takotsubo cardiomyopathy and sepsis: a systematic review [PDF]

, 2017
Takotsubo cardiomyopathy (TTC) is characterized by a systolic dysfunction localized in the apical and medial aspect of the left ventricle. It is usually related to physical or emotional stress.
Agarwal V, Costantino Ciallella, Geng S, Hutan Ashrafian, Lee S, Mariarosaria Aromatario, Maron BJ, Odigie-Okon E, Pullara A, Sarullo FM, Sato H, Sharkey SW, Sian Harding, Simone Cappelletti, Thanos Athanasiou, Xu RH   +15 more
core   +1 more source

Glucocorticoids in Sepsis: To Be or Not to Be

Frontiers in Immunology, 2020
Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle, Jolien Vandewalle, Claude Libert, Claude Libert   +3 more
openaire   +4 more sources

The atypical chemokine receptor ACKR2 is protective against sepsis [PDF]

, 2018
Sepsis is a systemic inflammatory response as a result of uncontrolled infections. Neutrophils are the first cells to reach the primary sites of infection and chemokines play a key role in recruiting neutrophils.
Alves-Filho, José Carlos, Amaral, Flávio Almeida, Borges, Vanessa, Castanheira, Fernanda Vargas E. Silva, Cunha, Fernando Queiroz, Cunha, Thiago Mattar, Donate, Paula Barbim, Graham, Gerard J., Kanashiro, Alexandre, Liew, Foo Y., Melo, Paulo Henrique, Pallas, Kenneth, Ramalho, Fernando Silva, Russo, Remo Castro, Sônego, Fabiane, Teixeira, Mauro Martins   +15 more
core   +1 more source

The Endothelium in Sepsis [PDF]

Shock, 2016
Sepsis affects practically all aspects of endothelial cell (EC) function and is thought to be the key factor in the progression from sepsis to organ failure. Endothelial functions affected by sepsis include vasoregulation, barrier function, inflammation, and hemostasis.
Ince, Can, Mayeux, Philip R., Nguyen, Trung, Gómez, Hernando, Kellum, John A., Ospina Tascón Gustavo A., Hernández P., Glenn, Murray, Patrick, De Backer, Daniel   +8 more
openaire   +7 more sources