Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
Scientific Reports, 2022 Observational studies have indicated an association between iron status and risk of sepsis and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of sepsis and risk of being hospitalized with COVID-19, performing a two ...
Randi Marie Mohus +8 more
doaj +1 more source
Delayed wound repair in sepsis is associated with reduced local pro-inflammatory cytokine expression [PDF]
, 2013 Sepsis is one of the main causes for morbidity and mortality in hospitalized patients. Moreover, sepsis associated complications involving impaired wound healing are common.
Albig, Michael +7 more
core +2 more sources
Circulating levels of micronutrients and risk of infections: a Mendelian randomization study
BMC Medicine, 2023 Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections.
Helene M. Flatby +4 more
doaj +1 more source
Antimicrobial Resistance in England 2017 to 2021 (ESPAUR Report 2021–22)
Medical Sciences Forum, 2023 The English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) antimicrobial resistance (AMR) chapter reports on bacterial, viral, and fungal AMR trends between 2017 and 2021 in England.
Rebecca Guy +9 more
doaj +1 more source
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]
, 2013 Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario +10 more
core +2 more sources
Takotsubo cardiomyopathy and sepsis: a systematic review [PDF]
, 2017 Takotsubo cardiomyopathy (TTC) is characterized by a systolic dysfunction localized in the apical and medial aspect of the left ventricle. It is usually related to physical or emotional stress.
Agarwal V +15 more
core +1 more source
Sphingolipidomics in Translational Sepsis Research–Biomedical Considerations and Perspectives
Frontiers in Medicine, 2021 Scientific Background: Sphingolipids are a highly diverse group of lipids with respect to physicochemical properties controlling either structure, distribution, or function, all of them regulating cellular response in health and disease.
Ralf A. Claus +3 more
doaj +1 more source
Identifying which septic patients have increased mortality risk using severity scores:a cohort study [PDF]
, 2014 Background: Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the performance of different severity
Davey, Peter G +5 more
core +4 more sources
Digital PCR applications for the diagnosis and management of infection in critical care medicine
Critical Care, 2022 Infection (either community acquired or nosocomial) is a major cause of morbidity and mortality in critical care medicine. Sepsis is present in up to 30% of all ICU patients.
Irene Merino +5 more
doaj +1 more source
Plasma adrenomedullin is associated with short-term mortality and vasopressor requirement in patients admitted with sepsis [PDF]
, 2014 Introduction: The incidence of death among patients admitted for severe sepsis or septic shock is high. Adrenomedullin (ADM) plays a central role in initiating the hyperdynamic response during the early stages of sepsis.
Bergmann A +5 more
core +1 more source