Results 31 to 40 of about 815,905 (331)

Sphingolipidomics in Translational Sepsis Research–Biomedical Considerations and Perspectives

Frontiers in Medicine, 2021
Scientific Background: Sphingolipids are a highly diverse group of lipids with respect to physicochemical properties controlling either structure, distribution, or function, all of them regulating cellular response in health and disease.
Ralf A. Claus, Markus H. Graeler, Markus H. Graeler, Markus H. Graeler   +3 more
doaj   +1 more source

Fine particulate matter pollution and risk of community-acquired sepsis [PDF]

, 2018
While air pollution has been associated with health complications, its effect on sepsis risk is unknown. We examined the association between fine particulate matter (PM2.5) air pollution and risk of sepsis hospitalization.
Al-Hamdan, Mohammad Z, Griffin, Russell, McClure, Leslie A, Moore, Justin Xavier, Sarmiento, Elisa J, Wang, Henry E   +5 more
core   +3 more sources

All that seems sepsis is not sepsis

Indian Journal of Critical Care Medicine, 2013
Catastrophic antiphospholipid antibody syndrome (CAPS) resembles severe sepsis in its acute presentation, with features of systemic inflammatory response syndrome (SIRS) leading to multiple organ dysfunction. Infections are the best known triggers of CAPS. This emphasizes the need for early diagnosis and aggressive treatment as the mortality is as high
Subramanian Shankar, Vivek S Guleria, Velu Nair, Prabhat Chauhan   +3 more
openaire   +4 more sources

Proteomic and epigenomic markers of sepsis-induced delirium (SID) [PDF]

, 2015
In elderly population sepsis is one of the leading causes of intensive care unit (ICU) admissions in the United States. Sepsis-induced delirium (SID) is the most frequent cause of delirium in ICU (Martin et al., 2010). Together delirium and SID represent
Adonis eSfera, Amy I Price, Carolina eOsorio, Michael eCummings, Roberto eGradini, Roberto eGradini   +5 more
core   +2 more sources

Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study. [PDF]

, 2019
BACKGROUND: Time to antibiotic administration is a key element in sepsis care; however, it is difficult to implement sepsis care bundles. Additionally, sepsis is different from other emergent conditions including acute coronary syndrome, stroke, or ...
Abe, T, Fujishima, S, Gando, S, Hagiwara, A, Hifumi, T, Ikeda, H, Iriyama, H, JAAM FORECAST group, Komori, A, Kotani, J, Kushimoto, S, Masuno, T, Mayumi, T, Naito, T, Nakada, T-A, Ogura, H, Okamoto, K, Otomo, Y, Phillips, GS, Rhodes, A, Saitoh, D, Sakamoto, Y, Sasaki, J, Shiino, Y, Shiraishi, A, Shiraishi, S-I, Sugiyama, T, Takeyama, N, Takuma, K, Tarui, T, Tokuda, Y, Tsuruta, R, Ueyama, M, Umemura, Y, Yamakawa, K, Yamashita, N   +35 more
core   +1 more source

Biomarkers for Sepsis [PDF]

BioMed Research International, 2014
Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful for monitoring the infectious process.
Henriquez-Camacho, Cesar, Losa, Juan
openaire   +4 more sources

Association between sepsis incidence and regional socioeconomic deprivation and health care capacity in Germany – an ecological study

BMC Public Health, 2021
Background Sepsis is a substantial health care burden. Data on regional variation in sepsis incidence in Germany and any possible associations with regional socioeconomic deprivation and health care capacity is lacking.
Norman Rose, Claudia Matthäus-Krämer, Daniel Schwarzkopf, André Scherag, Sebastian Born, Konrad Reinhart, Carolin Fleischmann-Struzek   +6 more
doaj   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

BMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta   +27 more
doaj   +1 more source

Glucocorticoids in Sepsis: To Be or Not to Be

Frontiers in Immunology, 2020
Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle, Jolien Vandewalle, Claude Libert, Claude Libert   +3 more
openaire   +4 more sources

Adsorption in sepsis [PDF]

Kidney International, 2000
The pathophysiology of sepsis offers a highly complicated scenario. In sepsis, endotoxin or other gram-positive-derived products induce a complex and dynamic cellular response, giving rise to several mediators known to be relevant in the pathogenesis of septic shock such as specific mediators, substances responsible for up- or down-regulation of ...
Ronco C, Brendolan A, Dan M, Piccinni P, Bellomo R, De Nitti C, Inguaggiato P, Tetta C   +7 more
openaire   +4 more sources