Results 51 to 60 of about 1,008,809 (397)
Detection of sepsis during emergency department triage using machine learning [PDF]
arXiv, 2022 Sepsis is a life-threatening condition with organ dysfunction and is a leading cause of death and critical illness worldwide. Even a few hours of delay in the treatment of sepsis results in increased mortality. Early detection of sepsis during emergency department triage would allow early initiation of lab analysis, antibiotic administration, and other
arxiv
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
, 2001 Background Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand.
Manuel +15 more
semanticscholar +1 more source
Glucocorticoids in Sepsis: To Be or Not to Be
Frontiers in Immunology, 2020 Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle +3 more
openaire +4 more sources
Kidney International, 2000 The pathophysiology of sepsis offers a highly complicated scenario. In sepsis, endotoxin or other gram-positive-derived products induce a complex and dynamic cellular response, giving rise to several mediators known to be relevant in the pathogenesis of septic shock such as specific mediators, substances responsible for up- or down-regulation of ...
Ronco C +7 more
openaire +4 more sources
Pediatric Critical Care Medicine, 2020 Supplemental Digital Content is available in the text. Objectives: To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ
S. Weiss +50 more
semanticscholar +1 more source
Critical Care, 2021 Polymorphonuclear neutrophils (PMNs) play an important role in sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived exosomes as a new subcellular entity acting as a fundamental link between PMN-driven inflammation and tissue
Yang Jiao +8 more
semanticscholar +1 more source
Presepsin is a novel highly effective sepsis marker (Review)
Сучасні медичні технології, 2020 In this review the most effective markers of septic process like Procalcitonin, C-reactive protein, and cytokines compared to the new marker – Presepsin (PSP) are analyzed.
S. D. Shapoval +3 more
doaj +1 more source
The epidemiology of sepsis in the United States from 1979 through 2000.
New England Journal of Medicine, 2003 BACKGROUND Sepsis represents a substantial health care burden, and there is limited epidemiologic information about the demography of sepsis or about the temporal changes in its incidence and outcome.
G. Martin +3 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic inflammation upon binding to pattern recognition receptors. Exosomes are endosome-derived vesicles, which carry proteins, lipids and nucleic acids, and facilitate intercellular
Atsushi Murao +6 more
openaire +4 more sources
Proteomic and epigenomic markers of sepsis-induced delirium (SID) [PDF]
, 2015 In elderly population sepsis is one of the leading causes of intensive care unit (ICU) admissions in the United States. Sepsis-induced delirium (SID) is the most frequent cause of delirium in ICU (Martin et al., 2010). Together delirium and SID represent
Adonis eSfera +5 more
core +2 more sources