Results 81 to 90 of about 875,517 (356)

Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]

open access: yes, 2016
Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F.   +4 more
core   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

open access: yesAdvanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt   +7 more
wiley   +1 more source

Innate immune training in the neonatal response to sepsis

open access: yesMolecular Medicine
Neonates, especially those born prematurely, are highly vulnerable to infection-induced mortality. Numerous observational and immunological studies in newborns have shown that live attenuated vaccines have beneficial, non-specific effects (NSEs) against ...
Jaimar C. Rincon   +12 more
doaj   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

open access: yesAdvanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal   +9 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Efficacy of mesenchymal stem cell therapy for sepsis: a meta-analysis of preclinical studies

open access: yesStem Cell Research & Therapy, 2020
Background Multiple studies have reported that mesenchymal stem cell (MSC) therapy has beneficial effects in experimental models of sepsis. However, this finding remains inconclusive.
Xue-Yi Sun   +7 more
doaj   +1 more source

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]

open access: yes, 2018
Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G.   +4 more
core   +1 more source

Recent Progress on Flexible Multimodal Sensors: Decoupling Strategies, Fabrication and Applications

open access: yesAdvanced Materials, EarlyView.
In this review, we establish a tripartite decoupling framework for flexible multimodal sensors, which elucidates the underlying principles of signal crosstalk and their solutions through material design, structural engineering, and AI algorithms. We also demonstrate its potential applications across environmental monitoring, health monitoring, human ...
Tao Wu   +10 more
wiley   +1 more source

Differential Interaction of Platelet-Derived Extracellular Vesicles With Circulating Immune Cells: Roles of TAM Receptors, CD11b, and Phosphatidylserine

open access: yesFrontiers in Immunology, 2018
Secretion and exchange of biomolecules by extracellular vesicles (EVs) are crucial in intercellular communication and enable cells to adapt to alterations in their microenvironment.
Birgit Fendl   +6 more
doaj   +1 more source

Neonatal sepsis [PDF]

open access: yesBiochemia Medica, 2011
Neonatal sepsis is the most common cause of neonatal deaths with high mortality despite treatment. Neonatal sepsis can be classified into two subtypes depending upon onset of symptoms. There are many factors that make neonates more susceptable to infection.
openaire   +4 more sources

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