Results 111 to 120 of about 1,083,142 (408)
Electrospinning and Nanofiber Technology: Fundamentals, Innovations, and Applications
Advanced Materials, EarlyView.This review explores electrospinning fundamentals, methods for synthesizing polymer, metal oxide, carbon, and composite nanofibers, and advancements in fiber architectures like porous, core–shell, and aligned structures. It highlights applications in functional membranes, sensors, energy systems, and catalyst design while addressing future ...
Yujang Cho +5 more
wiley +1 more source
Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis [PDF]
, 2019 BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis.
Bergmann, A. +4 more
core +1 more source
Annals of Medicine, 2002 Severe sepsis is a common disease process affecting some 2-11% of hospital admissions in the US. Severe sepsis and septic shock are associated with considerable morbidity and mortality, and account for a large part of intensive care unit costs.
Vincent, Jean Louis +2 more
openaire +3 more sources
Accelerated Bone Healing via Electrical Stimulation
Advanced Science, EarlyView.Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun +4 more
wiley +1 more source
Kidney & Blood Pressure Research, 2019 Background: Septic shock, the most serious complication of sepsis, is a life-threatening disease that is mainly characterized by hypoperfusion and multiple organ failure. Various aberrantly expressed microRNAs (miRNAs) have been reported to be related to
Lan Ling +4 more
doaj +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
Advanced Science, EarlyView.At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao +14 more
wiley +1 more source
Administration of ascorbic acid in the treatment of septic shock [PDF]
, 2021 Introduction: Septic shock is a common condition encountered in the intensive care unit. Sepsis is the leading cause of death with mortality ranging from 35-50%.
Kapadochos, Theodoros +3 more
core +1 more source
Advanced Science, EarlyView.Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei +15 more
wiley +1 more source
Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia
American Journal of Hematology, Volume 98, Issue 1, Page 122-130, January 2023., 2023 Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua +5 more
wiley +1 more source
Efficacy of 4-hour rescue therapeutic plasma exchange in severe septic shock patients
Romanian Journal of Internal Medicine, 2020 Background.Early intervention for septic shock is crucial to reduce mortality and improve outcome. There is still a great debate over the exact time of therapeutic plasma exchange (TPE) administration in septic shock patients.
Ahmed Rabab Mahmoud +4 more
doaj +1 more source