Results 81 to 90 of about 1,083,142 (408)

Septic Shock

Veterinary Clinics of North America: Small Animal Practice, 1989
Septic shock is a life-threatening condition that results from the combined effects of bacteria and the host's chemical mediators of inflammation. Of particular detriment is the hyperdynamic and hypodynamic vasomotor instability that severely compromises the patient prior to the onset of overt bacteremia.
Resident, From the Department of Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, Florida ( host institution ), Goodwin, John-Karl ( author ), Schaer, Michael ( author )   +2 more
openaire   +3 more sources

The Physiological Basis for Vitamin C as a Potential Treatment for Sepsis [PDF]

, 2019
Accounting for one third of all hospital patient deaths in America, sepsis remains one of the most deadly and complicated conditions that healthcare providers treat.
Johnston, Jennifer
core   +1 more source

A randomized trial of protocol-based care for early septic shock.

New England Journal of Medicine, 2014
BACKGROUND In a single-center study published more than a decade ago involving patients presenting to the emergency department with severe sepsis and septic shock, mortality was markedly lower among those who were treated according to a 6-hour protocol ...
D. Yealy, J. Kellum, David T. Huang, A. Barnato, L. Weissfeld, F. Pike, T. Terndrup, HE Wang, P. Hou, F. LoVecchio, M. Filbin, N. Shapiro, D. Angus   +12 more
semanticscholar   +1 more source

Management and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Post‐discharge management and outcomes of acute symptomatic seizures (ASyS) remain underexplored. We analyzed post‐discharge ASM management and outcomes in ASyS patients undergoing continuous EEG (cEEG), including the role of outpatient care through a post‐acute symptomatic seizure (PASS) clinic. Methods We performed a single‐center,
Vineet Punia, MarieElena Byrnes, Nicolas R. Thompson, Neishay Ayub, Clio Rubinos, Sahar Zafar, Adithya Sivaraju, Zhong Ying, Jessica R. Fesler, Stephen Hantus, Post‐Acute Symptomatic Seizure Investigation and Outcomes Network (PASSION) investigators   +10 more
wiley   +1 more source

Diagnostic value of Pentraxin-3 in patients with sepsis and septic shock in accordance with latest sepsis-3 definitions [PDF]

, 2017
Background: Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. This study assesses its diagnostic and prognostic value in patients with sepsis or septic shock in a medical intensive care unit (ICU). Methods:
A Mantovani, AP Wheeler, B Bottazzi, B Bottazzi, B Bottazzi, B Muller, C Garlanda, C Garlanda, C Henriquez-Camacho, DC Angus, Dominic Lepiorz, Dominic Pauly, E Rivers, F Bloos, F Breviarios, F Cuello, F Moalli, GW Lee, Ibrahim Akin, J Cohen, J Silvestre, M Behnes, M Shankar-Hari, M Singer, Martin Borggrefe, Max Barre, MD Kruif De, Michael Behnes, MM Levy, MM Levy, P Caironi, PC Reading, R Huttunen, R Uusitalo-Seppala, RC Bone, RP Dellinger, RP Dellinger, S Bastrup-Birk, S Bastrup-Birk, S Jaillon, S Kibe, S Liu, Siegfried Lang, Sonja Hamed, T Mauri, Thomas Bertsch, Tobias Becher, Ursula Hoffmann, W Knaus   +48 more
core   +1 more source

Sepsis and septic shock: Guideline-based management

Cleveland Clinic journal of medicine, 2020
Sepsis is a life-threatening organ dysfunction that results from the body’s response to infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection.
S. Dugar, Chirag Choudhary, A. Duggal
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Baseline Values of Left Ventricular Systolic Function in Preterm Infants With Septic Shock: A Prospective Observational Study

Frontiers in Pediatrics, 2022
Background and AimGuidelines recommended that cardiac index (CI) of term infants with septic shock should reach the target level of 3.3–6.0L/(min⋅m2). However, there are still no standard values for preterm infants with septic shock.
Junjuan Zhong, Chun Shuai, Yue Wang, Jing Mo, Dongju Ma, Jing Zhang, Yingyi Lin, Jie Yang, Xiuzhen Ye   +8 more
doaj   +1 more source

Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria [PDF]

, 2020
Introduction: The activity and regulation of inflammasome is receiving increasing attention in septic shock. Moreover, there is a growing body of evidence suggesting that mitochondrial DNA (mtDNA) can play a role as biomarker of disease severity and even
Busani, Stefano, Cossarizza, Andrea, De Biasi, Sara, Girardis, Massimo, Nasi, Milena, Paolini, Annamaria, Tosi, Martina, Venturelli, Sophie   +7 more
core   +1 more source

Direct Ink Writing of Conductive Hydrogels

Advanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho, Aline Braz Ramirez, Negar Akbarnia, Eric Croiset, Elisabeth Prince, Gerald G. Fuller, Milad Kamkar   +6 more
wiley   +1 more source