Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4. [PDF]
PLoS ONE, 2011 In the budding yeast Saccharomyces cerevisiae, the lysine acetyltransferase NuA4 has been linked to a host of cellular processes through the acetylation of histone and non-histone targets.
Leslie Mitchell +7 more
doaj +1 more source
The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms [PDF]
, 2008 © 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Ammerer G. +58 more
core +3 more sources
Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Advanced Science, Volume 12, Issue 38, October 13, 2025.Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu +11 more
wiley +1 more source
A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development. [PDF]
PLoS Genetics, 2015 Candida albicans is a major invasive fungal pathogen in humans. An important virulence factor is its ability to switch between the yeast and hyphal forms, and these filamentous forms are important in tissue penetration and invasion.
Diana M Calderón-Noreña +12 more
doaj +1 more source
An amphipathic helix enables septins to sense micrometer-scale membrane curvature [PDF]
, 2019 © The Authors, 2019. This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 International License.
Cannon, Kevin S. +3 more
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Electrochemical Science Advances, Volume 5, Issue 5, October 2025.ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley +1 more source
Analysis of Septin Reorganization at Cytokinesis Using Polarized Fluorescence Microscopy
Frontiers in Cell and Developmental Biology, 2017 Septins are conserved filament-forming proteins that act in diverse cellular processes. They closely associate with membranes and, in some systems, components of the cytoskeleton.
Molly McQuilken +8 more
doaj +1 more source
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation [PDF]
, 2014 Neurite growth requires two guanine nucleotide-binding protein polymers of tubulins and septins. However, whether and how those cytoskeletal systems are coordinated was unknown.
Ageta-Ishihara, Natsumi +9 more
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The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function
The Journal of Physiology, Volume 603, Issue 20, Page 5935-5964, October 15, 2025.Abstract figure legend The synaptic vesicle cluster acts as a master regulator of synaptic structure and function, through various involvements in processes that range from synaptic initiation to plasticity and synaptic loss. Abstract The synaptic vesicle cluster (SVC) is an essential component of chemical synapses, which provides neurotransmitter ...
Sofiia Reshetniak +35 more
wiley +1 more source
Septins: New Microtubule Interacting Partners [PDF]
The Scientific World JOURNAL, 2008 Originally characterized as regulators of cytokinesis, septins were later implicated in other cellular processes. Recent studies show that septins have a broader role in microtubule-dependent processes, such as karyokinesis, exocytosis, and maintenance of cell shape.
Rosalind Silverman-Gavrila +1 more
openaire +3 more sources