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Strategies for Multiple Sequence Alignment [PDF]

open access: goldBioTechniques, 2002
We present an overview of multiple sequence alignments to outline the practical consequences for the choices among different techniques and parameters. We begin with a discussion of the scoring methods for quantifying the quality of a multiple sequence ...
Hugh B. Nicholas   +2 more
doaj   +5 more sources

Optimal sequence alignments [PDF]

open access: greenProceedings of the National Academy of Sciences, 1983
Current theory is adequate to the task of finding an optimal alignment between two character strings such as nucleic acids. Most algorithms currently in use must fail to find the homologous alignment between a set of codons for the chicken α- and β-hemoglobin sequence when it is in fact discoverable by a more general treatment of gaps.
Walter M. Fitch, Temple F. Smith
openalex   +5 more sources

Sequence‐to‐sequence alignment using a pendulum [PDF]

open access: yesIET Computer Vision, 2015
Analysing two or more video sequences of dynamic scenes typically requires time synchronisation between sequences, where this alignment is not always possible using hardware.
Tomislav Pribanic   +2 more
doaj   +3 more sources

Developments in Algorithms for Sequence Alignment: A Review [PDF]

open access: yesBiomolecules, 2022
The continuous development of sequencing technologies has enabled researchers to obtain large amounts of biological sequence data, and this has resulted in increasing demands for software that can perform sequence alignment fast and accurately.
Jiannan Chao, Furong Tang, Lei Xu
doaj   +2 more sources

Shouji: A Fast and Efficient Pre-Alignment Filter for Sequence Alignment [PDF]

open access: yesBioinform., 2019
Motivation: The ability to generate massive amounts of sequencing data continues to overwhelm the processing capability of existing algorithms and compute infrastructures.
Alkan, Can   +4 more
core   +3 more sources

HELIOS: High-speed sequence alignment in optics. [PDF]

open access: yesPLoS Computational Biology, 2022
In response to the imperfections of current sequence alignment methods, originated from the inherent serialism within their corresponding electrical systems, a few optical approaches for biological data comparison have been proposed recently.
Ehsan Maleki   +2 more
doaj   +3 more sources

An Alignment Algorithm for Sequences [PDF]

open access: yesarXiv, 2012
This paper describes a new alignment algorithm for sequences that can be used for determination of deletions and substitutions. It provides several solutions out of which the best one can be chosen on the basis of minimization of gaps or other considerations.
Hosangadi, Sandeep, Kak, Subhash
arxiv   +3 more sources

OXBench: A benchmark for evaluation of protein multiple sequence alignment accuracy [PDF]

open access: goldBMC Bioinformatics, 2003
Background The alignment of two or more protein sequences provides a powerful guide in the prediction of the protein structure and in identifying key functional residues, however, the utility of any prediction is completely dependent on the accuracy of ...
Searle Stephen MJ   +4 more
doaj   +2 more sources

Pairwise Heuristic Sequence Alignment Algorithm Based on Deep Reinforcement Learning

open access: yesIEEE Open Journal of Engineering in Medicine and Biology, 2021
Goal: Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used method for comparative analysis of biological genomes.
Yong-Joon Song   +4 more
doaj   +1 more source

Efficient Multiple Sequences Alignment Algorithm Generation via Components Assembly Under PAR Framework

open access: yesFrontiers in Genetics, 2021
As a key algorithm in bioinformatics, sequence alignment algorithm is widely used in sequence similarity analysis and genome sequence database search.
Haipeng Shi   +3 more
doaj   +1 more source

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