Results 31 to 40 of about 608,924 (259)

Reticular alignment: A progressive corner-cutting method for multiple sequence alignment

open access: yesBMC Bioinformatics, 2010
Background In this paper, we introduce a progressive corner cutting method called Reticular Alignment for multiple sequence alignment. Unlike previous corner-cutting methods, our approach does not define a compact part of the dynamic programming table ...
Novák Ádám   +3 more
doaj   +1 more source

RNAmountAlign: Efficient software for local, global, semiglobal pairwise and multiple RNA sequence/structure alignment.

open access: yesPLoS ONE, 2020
Alignment of structural RNAs is an important problem with a wide range of applications. Since function is often determined by molecular structure, RNA alignment programs should take into account both sequence and base-pairing information for structural ...
Amir H Bayegan, Peter Clote
doaj   +1 more source

On the Edge of Web-Based Multiple Sequence Alignment Services

open access: yesTsinghua Science and Technology, 2012
There are many web-based multiple sequence alignment services accessible around the world. However, many researchers working on biological sequence analysis still struggle with inefficient, unfriendly user interface, and limited capability multiple ...
Ken D. Nguyen
doaj   +1 more source

Inverse parametric sequence alignment

open access: yesJournal of Algorithms, 2002
Summary: We consider the inverse parametric sequence alignment problem, where a sequence alignment, called a reference alignment, is given and the task is to determine parameter values such that the reference alignment is optimal for those parameter values.
Fangting Sun   +2 more
openaire   +3 more sources

Sequence Alignment as Hypothesis Testing [PDF]

open access: yesJournal of Computational Biology, 2011
Sequence alignment depends on the scoring function that defines similarity between pairs of letters. For local alignment, the computational algorithm searches for the most similar segments in the sequences according to the scoring function. The choice of this scoring function is important for correctly detecting segments of interest.
Lu Meng   +3 more
openaire   +2 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

gpALIGNER: A Fast Algorithm for Global Pairwise Alignment of DNA Sequences [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2011
Bioinformatics, through the sequencing of the full genomes for many species, is increasingly relying on efficient global alignment tools exhibiting both high sensitivity and specificity.
Mostafa Hadian Dehkordi   +2 more
doaj  

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia   +6 more
wiley   +1 more source

The effect of sequence quality on sequence alignment [PDF]

open access: yesBioinformatics, 2008
Abstract Motivation: The nucleotide sequencing process produces not only the sequence of nucleotides, but also associated quality values. Quality values provide valuable information, but are primarily used only for trimming sequences and generally ignored in subsequent analyses.
openaire   +2 more sources

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala   +8 more
wiley   +1 more source

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