Results 21 to 30 of about 4,572,181 (334)

A benchmark study of sequence alignment methods for protein clustering

open access: yesBMC Bioinformatics, 2018
Background Protein sequence alignment analyses have become a crucial step for many bioinformatics studies during the past decades. Multiple sequence alignment (MSA) and pair-wise sequence alignment (PSA) are two major approaches in sequence alignment ...
Yingying Wang, Hongyan Wu, Yunpeng Cai
doaj   +1 more source

Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction. [PDF]

open access: yes, 2006
BackgroundOne of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models.
Bourne, Philip E, Scheeff, Eric D
core   +3 more sources

MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization

open access: yesBriefings Bioinform., 2017
This article describes several features in the MAFFT online service for multiple sequence alignment (MSA). As a result of recent advances in sequencing technologies, huge numbers of biological sequences are available and the need for MSAs with large ...
K. Katoh   +2 more
semanticscholar   +1 more source

Spark-based Parallelization of Basic Local Alignment Search Tool [PDF]

open access: yesInternational Journal Bioautomation, 2020
Sequence alignment is a key link of bioinformatics analysis. The basic local alignment search tool (BLAST) is a popular sequence alignment algorithm with high accuracy. However, the BLAST is inefficient in comparing and analyzing a massive amount of gene
Hui Wang   +4 more
doaj   +1 more source

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

open access: yesMolecular biology and evolution, 2013
We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained ...
K. Katoh, D. Standley
semanticscholar   +1 more source

An enhanced RNA alignment benchmark for sequence alignment programs

open access: yesAlgorithms for Molecular Biology, 2006
Background The performance of alignment programs is traditionally tested on sets of protein sequences, of which a reference alignment is known. Conclusions drawn from such protein benchmarks do not necessarily hold for the RNA alignment problem, as was ...
Steger Gerhard   +2 more
doaj   +1 more source

The Sequence Alignment/Map format and SAMtools

open access: yesBioinform., 2009
Summary: The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms.
Heng Li   +8 more
semanticscholar   +1 more source

Bakta: rapid and standardized annotation of bacterial genomes via alignment-free sequence identification

open access: yesMicrobial Genomics, 2021
Command-line annotation software tools have continuously gained popularity compared to centralized online services due to the worldwide increase of sequenced bacterial genomes.
Oliver Schwengers   +5 more
semanticscholar   +1 more source

Accelerated large-scale multiple sequence alignment

open access: yesBMC Bioinformatics, 2011
Background Multiple sequence alignment (MSA) is a fundamental analysis method used in bioinformatics and many comparative genomic applications. Prior MSA acceleration attempts with reconfigurable computing have only addressed the first stage of ...
Lloyd Scott, Snell Quinn O
doaj   +1 more source

Sequence‐to‐sequence alignment using a pendulum

open access: yesIET Computer Vision, 2015
Analysing two or more video sequences of dynamic scenes typically requires time synchronisation between sequences, where this alignment is not always possible using hardware.
Tomislav Pribanic   +2 more
doaj   +1 more source

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