Results 1 to 10 of about 2,818,524 (302)
Integrative visual analysis of protein sequence mutations [PDF]
BMC Proceedings, 2014 An important aspect of studying the relationship between protein sequence, structure and function is the molecular characterization of the effect of protein mutations. To understand the functional impact of amino acid changes, the multiple biological properties of protein residues have to be considered together.Here, we present a novel visual approach ...
Doncheva, Nadezhda +5 more
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Interactive Analysis of Functional Residues in Protein Families
mSystems, 2022 A protein’s function depends on functional residues that determine its binding specificity or its catalytic activity, but these residues are typically not considered when annotating a protein’s function.
Morgan N. Price, Adam P. Arkin
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Analysis of the Sequence Characteristics of Antifreeze Protein
Life, 2021 Antifreeze protein (AFP) is a proteinaceous compound with improved antifreeze ability and binding ability to ice to prevent its growth. As a surface-active material, a small number of AFPs have a tremendous influence on the growth of ice.
Yu-Hang Zhang +7 more
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Protein sectors: statistical coupling analysis versus conservation [PDF]
, 2014 Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors".
Colwell, Lucy J. +2 more
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A sequence embedding method for enzyme optimal condition analysis
BMC Bioinformatics, 2020 Background An enzyme activity is influenced by the external environment. It is important to have an enzyme remain high activity in a specific condition.
Xiangjun Li +5 more
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STAR Protocols, 2023 Summary: Post-translational modifications (PTMs) serve as key regulatory mechanisms in various cellular processes; altered PTMs can potentially lead to human diseases.
Yu Yan +6 more
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BMC Bioinformatics, 2021 Background The use of sound to represent sequence data—sonification—has great potential as an alternative and complement to visual representation, exploiting features of human psychoacoustic intuitions to convey nuance more effectively.
Edward J. Martin +2 more
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MESSA: MEta-Server for protein Sequence Analysis
BMC Biology, 2012 Background Computational sequence analysis, that is, prediction of local sequence properties, homologs, spatial structure and function from the sequence of a protein, offers an efficient way to obtain needed information about proteins under study.
Cong Qian, Grishin Nick V
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Evolutionary Study of Protein Short Tandem Repeats in Protein Families
Biomolecules, 2023 Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion.
Pablo Mier, Miguel A. Andrade-Navarro
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ConSole: using modularity of contact maps to locate solenoid domains in protein structures. [PDF]
, 2014 BackgroundPeriodic proteins, characterized by the presence of multiple repeats of short motifs, form an interesting and seldom-studied group. Due to often extreme divergence in sequence, detection and analysis of such motifs is performed more reliably on
Godzik, Adam, Hrabe, Thomas
core +4 more sources