Results 1 to 10 of about 3,888,779 (212)
MESSA: MEta-Server for protein Sequence Analysis [PDF]
BMC Biology, 2012 Background Computational sequence analysis, that is, prediction of local sequence properties, homologs, spatial structure and function from the sequence of a protein, offers an efficient way to obtain needed information about proteins under study.
Cong Qian, Grishin Nick V
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Analysis of the Sequence Characteristics of Antifreeze Protein [PDF]
Life, 2021 Antifreeze protein (AFP) is a proteinaceous compound with improved antifreeze ability and binding ability to ice to prevent its growth. As a surface-active material, a small number of AFPs have a tremendous influence on the growth of ice.
Yu-Hang Zhang +7 more
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Coevolutionary Analysis of Protein Subfamilies by Sequence Reweighting [PDF]
Entropy, 2019 Extracting structural information from sequence co-variation has become a common computational biology practice in the recent years, mainly due to the availability of large sequence alignments of protein families.
Duccio Malinverni, Alessandro Barducci
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Analysis of Fbox substrate adapter proteins using ProteoSync, a program for projection of evolutionary conservation onto protein atomic coordinates [PDF]
Computational and Structural Biotechnology JournalThe projection of conservation onto the surface of a protein’s 3D structure is a powerful way of inferring functionally important regions. For this reason, we created ProteoSync, a Python program that semi-automates the process.
Elliot Sicheri +3 more
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Interactive Analysis of Functional Residues in Protein Families
mSystems, 2022 A protein’s function depends on functional residues that determine its binding specificity or its catalytic activity, but these residues are typically not considered when annotating a protein’s function.
Morgan N. Price, Adam P. Arkin
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A sequence embedding method for enzyme optimal condition analysis
BMC Bioinformatics, 2020 Background An enzyme activity is influenced by the external environment. It is important to have an enzyme remain high activity in a specific condition.
Xiangjun Li +5 more
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BMC Bioinformatics, 2021 Background The use of sound to represent sequence data—sonification—has great potential as an alternative and complement to visual representation, exploiting features of human psychoacoustic intuitions to convey nuance more effectively.
Edward J. Martin +2 more
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Analysis of protein chameleon sequence characteristics [PDF]
Bioinformation, 2009 Conversion of local structural state of a protein from an alpha-helix to a beta-strand is usually associated with a major change in the tertiary structure. Similar changes were observed during the self assembly of amyloidogenic proteins to form fibrils, which are implicated in severe diseases conditions, e.g., Alzheimer disease. Studies have emphasized
Ghozlane, Amine +3 more
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STAR Protocols, 2023 Summary: Post-translational modifications (PTMs) serve as key regulatory mechanisms in various cellular processes; altered PTMs can potentially lead to human diseases.
Yu Yan +6 more
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Evolutionary Study of Protein Short Tandem Repeats in Protein Families
Biomolecules, 2023 Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion.
Pablo Mier, Miguel A. Andrade-Navarro
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